Evidence map›Paper›PMID 33359413›Full record

ReviewNanomedicine : nanotechnology, biology, and medicine2021

CRISPR: A new paradigm of theranostics.

Neelam Yadav, Jagriti Narang, Anil Kumar Chhillar, Jogender Singh Rana

Abstract readReview
In one paragraph

Review in Nanomedicine : nanotechnology, biology, and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. A Rapid Visual Detection Method forAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. A critical review on therapeutic approaches of CRISPR-Cas9 in diabetes mellitus.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. The Challenge of CRISPR-Cas Toward Bioethics.Frontiers in microbiology · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neelam YadavDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana. Electronic address: neelamindia12@gmail.com.
Jagriti NarangDepartment of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, India. Electronic address: jags_biotech@yahoo.co.in.
Anil Kumar ChhillarCentre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana. Electronic address: anil.chhillar@gmail.com.
Jogender Singh RanaDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat. Electronic address: jsrana@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious and hereditary diseases are the primary cause of human mortality globally. Applications of conventional techniques require significant improvement in sensitivity and specificity in therapeutics. However, clustered regularly interspaced short palindromic repeats (CRISPRs) is an innovative genome editing technology which has provided a significant therapeutic tool exhibiting high sensitivity, fast and precise investigation of distinct pathogens in an epidemic. CRISPR technology has also facilitated the understanding of the biology and therapeutic mechanism of cancer and several other hereditary diseases. Researchers have used the CRISPR technology as a theranostic approach for a wide range of diseases causing pathogens including distinct bacteria, viruses, fungi and parasites and genetic mutations as well. In this review article, besides various therapeutic applications of infectious and hereditary diseases we have also explained the structure and mechanism of CRISPR tools and role of CRISPR integrated biosensing technology in provoking diagnostic applications.

Indexed as

AnimalsClustered Regularly Interspaced Short Palindromic RepeatsCommunicable DiseasesFungiGene EditingGenetic TherapyHumansMutationNeoplasmsParasitesPrecision MedicineVirusesBiosensing technologyCancerCardiovascular diseasesCRISPR technologyInfectious diseases

Identifiers

PMID33359413
PMCPMC7831819

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.