ReviewNeuropsychiatric disease and treatment2020
The Impact of Childhood Trauma on Developing Bipolar Disorder: Current Understanding and Ensuring Continued Progress.
Review in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- How is EMDR best conducted and adapted for trauma-focused work within bipolar disorder? A Delphi study.European journal of psychotraumatology · 2026Article
- Adverse childhood experiences and psychiatric outcomes among women with schizophrenia and depression in Singapore.European journal of psychotraumatology · 2026Article
- Childhood Maltreatment and Cognitive Performance in Bipolar Disorder: The Potential Role of Inflammation.Acta psychiatrica Scandinavica · 2026Article
- Key protective factors that mitigate the impact of childhood trauma on poor mental health in adulthood: a scoping review protocol.BMJ open · 2026Article
- The Effect of Childhood Trauma on the Alleviation of Transdiagnostic Depressive Symptoms and the Mediating Role of Resilience in Outpatient Adolescents.Journal of child & adolescent trauma · 2025Article
- Mechanisms of childhood trauma: an integrative review of a multimodal, transdiagnostic pathway.Neurobiology of stress · 2025Review
- A Transdiagnostic Network Analysis of Childhood Trauma and Psychopathology.Schizophrenia bulletin · 2025Article
- The effect of childhood trauma on bipolar depression.Scientific reports · 2025Article
- Neural subgroups in unaffected first-degree relatives of patients with bipolar disorder during emotion regulation.Psychological medicine · 2025Article
- Consumers with bipolar disorder presenting to an Australian child and youth mental health service.Frontiers in psychiatry · 2025Article
- Review
- Traumatic events in childhood and adulthood in a diverse-ancestry sample and their role in bipolar disorder.Psychiatry research · 2023Article
- Childhood trauma and neurocognitive functions in individuals with bipolar disorder and unaffected siblings of individuals with bipolar disorder.Neuroscience applied · 2023Article
- Interactive effects of polygenic risk and cognitive subtype on brain morphology in schizophrenia spectrum and bipolar disorders.European archives of psychiatry and clinical neuroscience · 2022Article
- Childhood trauma in bipolar disorder: new targets for future interventions.BJPsych open · 2022Article
- Influence of childhood maltreatment on prevalence, onset, and persistence of psychiatric comorbidities and suicide attempts in bipolar disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
- Using Microbiome-Based Approaches to Deprogram Chronic Disorders and Extend the Healthspan following Adverse Childhood Experiences.Microorganisms · 2022Review
- Combination Olanzapine and Samidorphan for the Management of Schizophrenia and Bipolar 1 Disorder in Adults: A Narrative Review.Health psychology research · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood trauma (CT) has been repeatedly linked to earlier onset and greater severity of bipolar disorder (BD) in adulthood. However, such knowledge is mostly based on retrospective and cross-sectional studies in adults with BD. The first objective of this selective review is to characterize the short-term effects of CT in the development of BD by focusing on studies in young people. The second objective is to describe the longer-term consequences of CT by considering studies with adult participants. This review first outlines the most prominent hypotheses linking CT exposure and the onset of BD. Then, it summarizes the psychological and biological risk factors implicated in the development of BD, followed by a discussion of original studies that investigated the role of CT in young people with early-onset BD, youths at increased risk of developing BD, or young people with BD with a focus on subclinical and clinical outcome measures. The review considers additional biological and psychological factors associated with a negative impact of CT on the long-term course of BD in later adulthood. Finally, we discuss how the integration of information of CT can improve ongoing early identification of BD and mitigate severe clinical expression in later adulthood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.