ReviewFrontiers in physiology2020
Building the Border: Development of the Chordate Neural Plate Border Region and Its Derivatives.
Review in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Reciprocal coupling between EMT and BMP morphogen signalling drives collective cell invasion.The EMBO journal · 2026Article
- Co-option and innovation in neural crest evolution.Science advances · 2026Review
- Single-cell, clonal and spatial atlases of cranial placodes illuminate their specification and evolution.bioRxiv : the preprint server for biology · 2026Article
- Dynamic and non-uniform expression of key transcription factors provides insights into the emergence of neural crest cells at the neural plate border.Development (Cambridge, England) · 2026Article
- An NKX2-5 homolog is required downstream of BMP signaling to pattern the sensory-adhesive organ of a tunicate larva.bioRxiv : the preprint server for biology · 2025Article
- Integrated Single-cell Analysis Uncovers Regulatory Logic of Cranial Ectoderm Development.bioRxiv : the preprint server for biology · 2025Article
- Small molecules direct the generation of ameloblast-like cells from human embryonic stem cells.Stem cell research & therapy · 2025Article
- Making sense of vertebrate senses from a neural crest and cranial placode evo-devo perspective.Trends in neurosciences · 2025Review
- Holoprosencephaly and cyclopia inAnimal cells and systems · 2025Article
- From neural crest migration to the onset of gangliogenesis.Current topics in developmental biology · 2025Review
- SoxB1 transcription factors are essential for initiating and maintaining neural plate border gene expression.Development (Cambridge, England) · 2024Article
- A time-resolved single-cell roadmap of the logic driving anterior neural crest diversification from neural border to migration stages.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- In vitro induction of patterned branchial arch-like aggregate from human pluripotent stem cells.Nature communications · 2024Article
- Sensory cells in tunicates: insights into mechanoreceptor evolution.Frontiers in cell and developmental biology · 2024Review
- The genomic landscape of mammal domestication might be orchestrated by selected transcription factors regulating brain and craniofacial development.Development genes and evolution · 2023Article
- The Foxi3 transcription factor is necessary for the fate restriction of placodal lineages at the neural plate border.Development (Cambridge, England) · 2023Article
- Review
- Early Steps towards Hearing: Placodes and Sensory Development.International journal of molecular sciences · 2023Review
- Ndst1, a heparan sulfate modification enzyme, regulates neuroectodermal patterning by enhancing Wnt signaling in Xenopus.Development, growth & differentiation · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The paired cranial sensory organs and peripheral nervous system of vertebrates arise from a thin strip of cells immediately adjacent to the developing neural plate. The neural plate border region comprises progenitors for four key populations of cells: neural plate cells, neural crest cells, the cranial placodes, and epidermis. Putative homologues of these neural plate border derivatives can be found in protochordates such as amphioxus and tunicates. In this review, we summarize key signaling pathways and transcription factors that regulate the inductive and patterning events at the neural plate border region that give rise to the neural crest and placodal lineages. Gene regulatory networks driven by signals from WNT, fibroblast growth factor (FGF), and bone morphogenetic protein (BMP) signaling primarily dictate the formation of the crest and placodal lineages. We review these studies and discuss the potential of recent advances in spatio-temporal transcriptomic and epigenomic analyses that would allow a mechanistic understanding of how these signaling pathways and their downstream transcriptional cascades regulate the formation of the neural plate border region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.