ArticleEpigenetics2021
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample.
Article in Epigenetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- CircRNA profiles from one-tube multiplex probe-based qPCR can distinguish between monozygotic twins.International journal of legal medicine · 2026Article
- DNA methylation signatures associated with early-onset schizophrenia in Chinese patients.Translational psychiatry · 2026Article
- MicroBayesAge: a maximum likelihood approach to predict epigenetic age using microarray data.GeroScience · 2026Article
- Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism.Scientific reports · 2026Article
- The Peripheral Epigenome Predicts White Matter Volume Contingent on Developmental Stage: An ECHO Study.Molecular neurobiology · 2025Article
- A Pilot Epigenome-Wide Study of Posttraumatic Growth: Identifying Novel Candidates for Future Research.Epigenomes · 2025Article
- Development and validation of a novel cell type estimation method for targeted bisulfite sequencing data.Epigenomics · 2025Article
- Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.Nature communications · 2024Article
- Development of an epigenetic clock resistant to changes in immune cell composition.Communications biology · 2024Article
- Technical strategy for monozygotic twin discrimination by single-nucleotide variants.International journal of legal medicine · 2024Article
- The association between DNA methylation and human height and a prospective model of DNA methylation-based height prediction.Human genetics · 2024Article
- Loss of function inGenetics in medicine open · 2024Article
- Alterations in DNA methylation associate with reduced migraine and headache days after medication withdrawal treatment in chronic migraine patients: a longitudinal study.Clinical epigenetics · 2023Article
- Accurate age prediction from blood using a small set of DNA methylation sites and a cohort-based machine learning algorithm.Cell reports methods · 2023Article
- Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort.The Lancet. Child & adolescent health · 2023Article
- Can epigenetics shine a light on the biological pathways underlying major mental disorders?Psychological medicine · 2022Review
- Understanding Health Inequalities Through the Lens of Social Epigenetics.Annual review of public health · 2022Review
- Histochemistry, Cytochemistry and Epigenetics.Acta histochemica et cytochemica · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
Accumulating evidence suggests that individuals exposed to victimization at key developmental stages may have different epigenetic fingerprints compared to those exposed to no/minimal stressful events, however results are inconclusive. This study aimed to strengthen causal inference regarding the impact of adolescent victimization on the epigenome by controlling for genetic variation, age, gender, and shared environmental exposures. We conducted longitudinal epigenome-wide association analyses (EWAS) on DNA methylation (DNAm) profiles of 118 monozygotic (MZ) twin pairs from the Environmental Risk study with and without severe adolescent victimization generated using buccal DNA collected at ages 5, 10 and 18, and the Illumina EPIC array. Additionally, we performed cross-sectional EWAS on age-18 blood and buccal DNA from the same individuals to elucidate tissue-specific signatures of severe adolescent victimization. Our analyses identified 20 suggestive differentially methylated positions (DMPs) (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.