Evidence map›Paper›PMID 33374096›Full record

ArticleJournal of clinical research in pediatric endocrinology2021

Basal Serum Thyroxine Level should Guide Initial Thyroxine Replacement Dose in Neonates with Congenital Hypothyroidism

Ceren Günbey, Alev Özön, E Nazlı Gönç, Ayfer Alikaşifoğlu, Sevilay Karahan, Nurgün Kandemir

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ceren GünbeyHacettepe University Faculty of Medicine, Department of Pediatric Neurology, Ankara, TurkeyORCID 0000-0003-2244-828X
Alev ÖzönHacettepe University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0002-2390-5123
E Nazlı GönçHacettepe University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0003-1385-2563
Ayfer AlikaşifoğluHacettepe University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0003-3379-6407
Sevilay KarahanHacettepe University Faculty of Medicine, Department of Biostatistics, Ankara, TurkeyORCID 0000-0002-8692-7266
Nurgün KandemirHacettepe University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0002-6345-9770
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Initial high-dose sodium levothyroxine (Na-LT Methods: Fifty-two patients were analyzed retrospectively. The patients were classified into mild (27/51.9%), moderate (11/21.1%) and severe (14/26.9%) CH, based on initial free thyroxine (fT Results: Initial mean Na-LT Conclusion: Not all patients diagnosed with CH require high-dose Na-LT

Indexed as

Hormone Replacement TherapyBiomarkersClinical Decision-MakingCongenital HypothyroidismFemaleHumansHyperthyroxinemiaIatrogenic DiseaseInfant, NewbornMaleNeonatal ScreeningRetrospective StudiesRisk AssessmentRisk FactorsThyroxineTreatment OutcomeBiomarkersThyroxinechildrencongenital hypothyroidismdoseNa-L thyroxineNewborn screening

Identifiers

PMID33374096
PMCPMC8388053
OpenAlexW3115075656

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.