Evidence map›Paper›PMID 33375263›Full record

ReviewCells2020

New Molecular Players in the Development of Callosal Projections.

Ray Yueh Ku, Masaaki Torii

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  6. Article
  7. The Impact of theDiagnostics (Basel, Switzerland) · 2023
    Article
  8. Differential impacts ofFrontiers in neuroscience · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ray Yueh KuCenter for Neuroscience Research, Children's Research Institute, Children's National Hospital, Washington, DC 20010, USA.ORCID 0000-0002-9958-0716
Masaaki ToriiCenter for Neuroscience Research, Children's Research Institute, Children's National Hospital, Washington, DC 20010, USA.ORCID 0000-0003-0162-7924
Children's National · US

Funding

Role of autism-linked genes in developmental refinement of the corpus callosumR01MH111674 · NIMH · CHILDREN'S RESEARCH INSTITUTE · PI TORII, MASAAKI · 2017 to 2021
$2.4M
Mechanisms and treatments of learning deficits in Fetal Alcohol Spectrum DisordersR01AA026272 · NIAAA · CHILDREN'S RESEARCH INSTITUTE · PI HASHIMOTO-TORII, KAZUE, TORII, MASAAKI · 2019 to 2023
$2.4M
Investigating the effect of alcohol exposure on human cortical development using a 3D in vitro modelF32AA028163 · NIAAA · CHILDREN'S RESEARCH INSTITUTE · PI KU, RAY YUEH · 2019 to 2023
$214k
NIAAA NIH HHS F32 AA028163NIMH NIH HHS R01 MH111674
6 · The paper itself

Abstract

Cortical development in humans is a long and ongoing process that continuously modifies the neural circuitry into adolescence. This is well represented by the dynamic maturation of the corpus callosum, the largest white matter tract in the brain. Callosal projection neurons whose long-range axons form the main component of the corpus callosum are evolved relatively recently with a substantial, disproportionate increase in numbers in humans. Though the anatomy of the corpus callosum and cellular processes in its development have been intensively studied by experts in a variety of fields over several decades, the whole picture of its development, in particular, the molecular controls over the development of callosal projections, still has many missing pieces. This review highlights the most recent progress on the understanding of corpus callosum formation with a special emphasis on the novel molecular players in the development of axonal projections in the corpus callosum.

Indexed as

Corpus CallosumAnimalsAxonsHumansNeuronsProteinsProteinscallosal projectionscerebral cortexcorpus callosumcortical neuronsdevelopment

Identifiers

PMID33375263
PMCPMC7824101
OpenAlexW3114008714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.