Evidence map›Paper›PMID 33379351›Full record

ReviewInternational journal of molecular sciences2020

Pathological Insight into 5-HT

Anna Löfdahl, Göran Tornling, Jenny Wigén, Anna-Karin Larsson-Callerfelt, Christina Wenglén, Gunilla Westergren-Thorsson

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Observational
  2. The Extract ofFood science & nutrition · 2026
    Article
  3. Article
  4. Article
  5. DualACS medicinal chemistry letters · 2024
    Article
  6. Structure activity relationships of 5-HTEuropean journal of medicinal chemistry · 2023
    Article
  7. Article
  8. Pathophysiology of the Serotonin System in the Nervous System and Beyond.International journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna LöfdahlLung Biology, Department of Experimental Medical Science, Lund University, BMC C12, 22184 Lund, Sweden.
Göran TornlingAnaMar AB, Medicon Village, Scheeletorget 1, 22381 Lund, Sweden.
Jenny WigénLung Biology, Department of Experimental Medical Science, Lund University, BMC C12, 22184 Lund, Sweden.
Anna-Karin Larsson-CallerfeltLung Biology, Department of Experimental Medical Science, Lund University, BMC C12, 22184 Lund, Sweden.ORCID 0000-0001-7586-3896
Christina WenglénAnaMar AB, Medicon Village, Scheeletorget 1, 22381 Lund, Sweden.
Gunilla Westergren-ThorssonLung Biology, Department of Experimental Medical Science, Lund University, BMC C12, 22184 Lund, Sweden.
Lund University · SEKarolinska Institutet · SEMedicon Village · SE

Funding

ALF -Royal Physiographic Society of Lund -Swedish foundation for Strategic Research SBE13-0130Swedish Heart-Lung Foundation 20140293Swedish Research Council in Medicine and Health 11550, 2016-01190the Åke och Inger Bergkvist foundation -the Alfred Österlund Foundation -the Crafoord Foundation -the Greta and John Kock Foundation -the Medical Faculty of Lund University -the Olle Engkvist Foundation -VR3R 2016-01190
6 · The paper itself

Abstract

Interstitial lung disease (ILD) encompasses a heterogeneous group of more than 200 conditions, of which primarily idiopathic pulmonary fibrosis (IPF), idiopathic nonspecific interstitial pneumonia, hypersensitivity pneumonitis, ILD associated with autoimmune diseases and sarcoidosis may present a progressive fibrosing (PF) phenotype. Despite different aetiology and histopathological patterns, the PF-ILDs have similarities regarding disease mechanisms with self-sustaining fibrosis, which suggests that the diseases may share common pathogenetic pathways. Previous studies show an enhanced activation of serotonergic signaling in pulmonary fibrosis, and the serotonin (5-HT)

Indexed as

AnimalsHumansIdiopathic Pulmonary FibrosisInflammationLung Diseases, InterstitialModels, BiologicalReceptor, Serotonin, 5-HT2BSerotonin 5-HT2 Receptor AntagonistsReceptor, Serotonin, 5-HT2BSerotonin 5-HT2 Receptor Antagonists5-HT5-HT2B receptor antagonismfibrosisILD

Identifiers

PMID33379351
PMCPMC7796180
OpenAlexW3118197300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.