Evidence map›Paper›PMID 33381606›Full record

ReviewJournal of immunology research2020

The Function and Role of the Th17/Treg Cell Balance in Inflammatory Bowel Disease.

Jun-Bin Yan, Min-Min Luo, Zhi-Yun Chen, Bei-Hui He

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed, 4 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

193 citing papers in PubMed, 4 syntheses or guidelines pooled it, 335 citations in OpenAlex.

  1. Pooled it
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  13. The role and mechanism of IL‑35 in myasthenia gravis (Review).International journal of molecular medicine · 2026
    Review
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  17. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
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  19. Review
  20. Veterinary sciences · 2026
    Article

133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jun-Bin YanThe Second Central Laboratory, Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circulatory Diseases of Zhejiang Province, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.ORCID https://orcid.org/0000-0001-5014-7156
Min-Min LuoThe Second Central Laboratory, Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circulatory Diseases of Zhejiang Province, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.ORCID https://orcid.org/0000-0002-7519-0844
Zhi-Yun ChenThe Second Central Laboratory, Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circulatory Diseases of Zhejiang Province, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.ORCID https://orcid.org/0000-0002-2072-444X
Bei-Hui HeThe Second Central Laboratory, Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circulatory Diseases of Zhejiang Province, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.ORCID https://orcid.org/0000-0001-6170-8481
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic, inflammatory, and autoimmune disorder. The pathogenesis of IBD is not yet clear. Studies have shown that the imbalance between T helper 17 (Th17) and regulatory T (Treg) cells, which differentiate from CD4

Indexed as

Lymphocyte CountAnimalsBile Acids and SaltsBiomarkersCytokinesDisease SusceptibilityGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesRisk FactorsSignal TransductionTh17 CellsT-Lymphocytes, RegulatoryBile Acids and SaltsBiomarkersCytokines

Identifiers

PMID33381606
PMCPMC7755495
OpenAlexW3112156861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.