Evidence map›Paper›PMID 33391978›Full record

ArticleNanotheranostics2021

Resveratrol loaded polymeric micelles for theranostic targeting of breast cancer cells.

Yiota Gregoriou, Gregoria Gregoriou, Vural Yilmaz, Konstantinos Kapnisis, Marianna Prokopi, Andreas Anayiotos, Katerina Strati, Nikolas Dietis, Andreas I Constantinou, Chrysafis Andreou

Abstract read
In one paragraph

Article in Nanotheranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Application of nanoparticles in breast cancer treatment: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yiota GregoriouDepartment of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus.
Gregoria GregoriouDepartment of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus.
Vural YilmazDepartment of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus.
Konstantinos KapnisisDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Marianna ProkopiDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Andreas AnayiotosDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Katerina StratiDepartment of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus.
Nikolas DietisMedical School University of Cyprus, Nicosia, Cyprus.
Andreas I ConstantinouDepartment of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus.
Chrysafis AndreouDepartment of Electrical and Computer Engineering University of Cyprus, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of breast cancer underwent extensive progress in recent years with molecularly targeted therapies. However, non-specific pharmaceutical approaches (chemotherapy) persist, inducing severe side-effects. Phytochemicals provide a promising alternative for breast cancer prevention and treatment. Specifically, resveratrol (res) is a plant-derived polyphenolic phytoalexin with potent biological activity but displays poor water solubility, limiting its clinical use. Here we have developed a strategy for delivering res using a newly synthesized nano-carrier with the potential for both diagnosis and treatment.

Indexed as

Drug CarriersMicellesAntineoplastic AgentsBreast NeoplasmsFemaleHumansMCF-7 CellsResveratrolAntineoplastic AgentsDrug CarriersMicellesResveratrolbreast cancercancer nanomedicinedrug-deliverynanotheranosticsresveratrol

Identifiers

PMID33391978
PMCPMC7738945

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.