Evidence map›Paper›PMID 33392263›Full record

ReviewFrontiers in molecular biosciences2020

The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic.

Ludwig Aigner, Frank Pietrantonio, Diana Marisa Bessa de Sousa, Johanna Michael, Daniela Schuster, Herbert Anton Reitsamer, Horst Zerbe, Michael Studnicka

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
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  6. Review
  7. Review
  8. Article
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  11. Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. TEGJournal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ludwig AignerInstitute of Molecular Regenerative Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria.
Frank PietrantonioIntelGenx Co5rp., Saint-Laurent, QC, Canada.
Diana Marisa Bessa de SousaInstitute of Molecular Regenerative Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria.
Johanna MichaelInstitute of Molecular Regenerative Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria.
Daniela SchusterDepartment of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University Salzburg, Salzburg, Austria.
Herbert Anton ReitsamerDepartment of Ophthalmology and Optometry, University Clinic Salzburg, Paracelsus Medical University, Salzburg, Austria.
Horst ZerbeIntelGenx Co5rp., Saint-Laurent, QC, Canada.
Michael StudnickaDepartment of Pulmonary Medicine, University Clinic Salzburg, Paracelsus Medical University Salzburg, Salzburg, Austria.
Paracelsus Medical University · ATAustrian Cluster for Tissue Regeneration · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence and global impact of COVID-19 has focused the scientific and medical community on the pivotal influential role of respiratory viruses as causes of severe pneumonia, on the understanding of the underlying pathomechanisms, and on potential treatment for COVID-19. The latter concentrates on

Indexed as

COVID-19inflammationleukotriene receptor antagonist (LTRA)leukotrienesviral pneumonia

Identifiers

PMID33392263
PMCPMC7773944
OpenAlexW3118932141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.