GuidelineInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2021
ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma.
5 registry-linked trialsAbstract readPractice Guideline
In one paragraph
Guideline in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 865 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
865citing papers in PubMed, 5 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SHAPE-ENDO (Strategic Hormonal Approach & Prehabilitation in Endometrial Cancer): An Open-Label, Pilot Randomized Clinical Trial Comparing Standard Immediate Surgery Versus a Multimodal Metabolic Optimization and Prehabilitation Strategy Before Surgery in Patients With Atypical Endometrial Hyperplasia or Low-Risk Endometrioid Endometrial Cancer and BMI ≥40 kg/m²
PMID 33755728PMID 33667417PMID 36216945PMID 40768192PMID 40744042PMID 40316173PMID 39429275PMID 38764577PMID 36326317PMID 35314087PMID 34238643PMID 30193337other papers from this trial
Open the trial in the graphRandomized Phase III Trial of Molecular Profile-based Versus Standard Recommendations for Adjuvant Therapy for Women With Early Stage Endometrioid Adenocarcinoma
Randomized Controlled Trial on the Oncologic Outcomes of Use Versus Not Use of the Uterine Manipulator in the Surgical Treatment of Apparent Uterine-confined Endometrial Carcinoma
One Step Nucleic Acid Amplification (OSNA) Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer: a Randomized, Multicenter, Controlled Trial (SENT-OSNA Study)
Perioperative Outcomes of Surgical Staging in Patients With Early-stage Endometrial Carcinoma: Comparison Between Laparoscopy and Laparotomy in a Low-resource Setting
Who cites it
865 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Diagnostic accuracy of phosphatase and tensin homolog loss in differentiating between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia and non-atypical endometrial hyperplasia: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Pooled it
- Minimally invasive surgical treatment of recurrent endometrial carcinoma: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Pooled it
- TCGA molecular subtypes in endometriosis-associated ovarian cancer: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Efficacy of dostarlimab in recurrent or advanced mismatch Repair-Deficient endometrial Cancer as a Single-Agent therapy: A systematic review and Meta-Analysis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025Pooled it
- Evolution of lymphovascular space invasion in early-stage endometrial carcinoma: stratification, quantification, and clinical implications: a systematic review.Archives of gynecology and obstetrics · 2025Pooled it
- Sentinel node detection and imaging concordance in Early-Stage ovarian cancer: A MELISA trial analysis of tracer, timing, and intraoperative gamma camera.European journal of nuclear medicine and molecular imaging · 2026Trial
- Real-world demographics and survival outcomes of patients in England with advanced or recurrent endometrial cancer by mismatch repair status.Gynecologic oncology reports · 2026Article
- Molecular classification-driven stage migration and prognostic risk stratification in endometrial cancers: FIGO 2023 vs FIGO 2009.Virchows Archiv : an international journal of pathology · 2026Article
- Molecular subtypes and survival patterns of endometrial cancer in a South Indian cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Characterization of immune landscape and prognostic value of IL-17-related signature in uterine corpus endometrial carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Prevalence of Mismatch Repair Deficiency and Its Association with Histopathological Parameters in Endometrial Cancer: A Prospective Cohort Study.International journal of molecular sciences · 2026Article
- The Impact of Molecular Profile Changes and Other Histopathological Parameters on Endometrial Cancer Recurrence.Cancers · 2026Article
- Evolving paradigms in lymph node surgery in endometrial cancer: insights from the multicenter E-PEC trial.Archives of gynecology and obstetrics · 2026Article
- Assisted Reproductive Technology in Breast and Gynecologic Malignancies: Cancer Risk, Fertility Preservation, and Post-Treatment Reproductive Outcomes.Journal of clinical medicine · 2026Review
- Predictive Value of Preoperative Endometrial Thickness for Concurrent Endometrial Carcinoma in Patients with Endometrial Intraepithelial Neoplasia.Journal of clinical medicine · 2026Article
- Deciphering survival disparities in endometrial cancer: a focus on mismatch repair pathway integrity (systematic review and meta-analysis).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Substantial LVSI Is Independently Associated with Para-Aortic Nodal Metastasis in Patients Undergoing Laparoscopic Surgical Staging for Endometrial Cancer.Current oncology (Toronto, Ont.) · 2026Article
- Article
- From Molecular Classification to Hereditary Cancer Syndrome Identification in Endometrial Cancer.Genes · 2026Article
- Concordance between multidisciplinary tumor board decisions and AI-based recommendations in endometrial cancer: impact of discordance direction on clinical outcomes.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
805 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
28 authors.
Nicole ConcinDepartment of Gynecology and Obstetrics, Innsbruck Medical University, Innsbruck, Austria nicole.concin@i-med.ac.at.ORCID 0000-0002-9795-2643
Xavier Matias-GuiuDepartment of Pathology, Hospital Universitari Arnau de Vilanova, University of Lleida, CIBERONC, Irblleida, Spain.
Ignace VergoteDepartment of Gynecology and Obstetrics, Gynecologic Oncology, Leuven Cancer Institute, Catholic University Leuven, Leuven, Belgium.
David CibulaDepartment of Obstetrics and Gynecology, First Faculty of Medicine, Charles University, General University Hospital in Prague, Prague, Czech Republic.
Mansoor Raza MirzaDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Simone MarnitzDepartment of Radiation Oncology, Medical Faculty of the University of Cologne, Cologne, Germany.
Jonathan LedermannUCL Cancer Institute, University College, London, UK.ORCID 0000-0003-3799-3539
Tjalling BosseDepartment of Pathology, Leids Universitair Medisch Centrum, Leiden, Netherlands.
Cyrus ChargariDepartment of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
Anna FagottiDivision of Gynecologic Oncology, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Christina FotopoulouDepartment of Gynaecologic Oncology, Imperial College London Faculty of Medicine, London, UK.ORCID 0000-0001-6375-9645
Antonio Gonzalez MartinDepartment of Medical Oncology, Clinica Universidad de Navarra, Madrid, Spain.
Sigurd LaxDepartment of Pathology, Hospital Graz II, Graz, Austria.
Domenica LorussoDivision of Gynecologic Oncology, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Christian MarthDepartment of Obstetrics and Gynecology, Innsbruck Medical University, Innsbruck, Austria.
Philippe MoriceDepartment of Surgery, Institut Gustave Roussy, Villejuif, France.
Remi A NoutDepartment of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Dearbhaile O'DonnellDepartment of Medical Oncology, St James Hospital, Dublin, Ireland.
Denis QuerleuDivision of Gynecologic Oncology, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-3984-4812
Maria Rosaria RaspolliniHistopathology and Molecular Diagnostics, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
Jalid SehouliDepartment of Gynecology with Center for Oncological Surgery, Campus Virchow Klinikum, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Alina SturdzaDepartment of Radiation Oncology, Comprehensive Cancer Center, Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, Vienna, Austria.
Alexandra TaylorDepartment of Gynaecology, Royal Marsden Hospital, London, UK.
Anneke WestermannDepartment of Medical Oncology, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, Netherlands.
Pauline WimbergerDepartment of Gynecology and Obstetrics, TU Dresden Medizinische Fakultat Carl Gustav Carus, Dresden, Germany.
Nicoletta ColomboGynecologic Oncology Program, European Institute of Oncology, IRCCS, Milan and University of Milan-Bicocca, Milan, Italy.
François PlanchampClinical Research Unit, Institut Bergonie, Bordeaux, France.
Carien L CreutzbergDepartment of Radiation Oncology, Leiden University Medical Center, Leiden, Netherlands.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A European consensus conference on endometrial carcinoma was held in 2014 to produce multi-disciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy and Oncology (ESTRO), and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide.
Indexed as
Endometrial NeoplasmsEuropeFemaleGenital Neoplasms, FemaleHumansMedical OncologyPreoperative CareRisk Factorspathologyradiationsurgeryuterine cancer
Identifiers
PMID
33397713What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
NCT07462663ClinicalTrials.gov
NCT05179447ClinicalTrials.gov
NCT05687084ClinicalTrials.gov
NCT06935305ClinicalTrials.gov
NCT07546825ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.