Evidence map›Paper›PMID 33401689›Full record

ArticleInternational journal of molecular sciences2021

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing.

Ruirui Lu, Katharina Metzner, Fangyuan Zhou, Cathrin Flauaus, Annika Balzulat, Patrick Engel, Jonas Petersen, Rebekka Ehinger, Anne Bausch, Peter Ruth and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ruirui LuInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Katharina MetznerInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Fangyuan ZhouInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Cathrin FlauausInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Annika BalzulatInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Patrick EngelInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Jonas PetersenInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Rebekka EhingerPharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Anne BauschPharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Peter RuthPharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Robert LukowskiPharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Achim SchmidtkoInstitut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Goethe University Frankfurt · DEUniversity of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft LU 2514/1-1the Else Kröner-Fresenius-Stiftung 2018_A95
6 · The paper itself

Abstract

The sodium-activated potassium channel Slack (K

Indexed as

Adenosine TriphosphateAnimalsBehavior Rating ScaleCalciumGanglia, SpinalMiceMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsNeuralgiaPatch-Clamp TechniquesPeripheral NervesPotassium ChannelsPotassium Channels, Sodium-ActivatedReceptors, Purinergic P2X3Sensory Receptor CellsAdenosine Triphosphatealpha,beta-methyleneadenosine 5'-triphosphateCalciumNerve Tissue ProteinsPotassium ChannelsPotassium Channels, Sodium-ActivatedReceptors, Purinergic P2X3Slo2 protein, mousedorsal root gangliamiceneuropathic painP2X3Slack

Identifiers

PMID33401689
PMCPMC7795269
OpenAlexW3118616657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.