Evidence map›Paper›PMID 33402422›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Structural and Functional Synaptic Plasticity Induced by Convergent Synapse Loss in the

Yupu Wang, Meike Lobb-Rabe, James Ashley, Veera Anand, Robert A Carrillo

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

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  9. Neuromuscular basis ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. bioRxiv : the preprint server for biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yupu WangDepartment of Molecular Genetics & Cellular Biology, University of Chicago, Chicago, Illinois 60637.ORCID 0000-0002-3553-0680
Meike Lobb-RabeDepartment of Molecular Genetics & Cellular Biology, University of Chicago, Chicago, Illinois 60637.ORCID 0000-0001-6486-7752
James AshleyDepartment of Molecular Genetics & Cellular Biology, University of Chicago, Chicago, Illinois 60637.ORCID 0000-0002-6693-1014
Veera AnandDepartment of Molecular Genetics & Cellular Biology, University of Chicago, Chicago, Illinois 60637.
Robert A CarrilloDepartment of Molecular Genetics & Cellular Biology, University of Chicago, Chicago, Illinois 60637 robertcarrillo@uchicago.edu.ORCID 0000-0002-2067-9861
University of Illinois Chicago · USUniversity of Chicago · US

Funding

Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Interactions Between IgSF Proteins in Neural Circuit FormationK01NS102342 · NINDS · UNIVERSITY OF CHICAGO · PI CARRILLO, ROBERT ARNULFO · 2017 to 2019
$684k
DIP-α is required for synaptic elaboration and functionF31NS120458 · NINDS · UNIVERSITY OF CHICAGO · PI LOBB-RABE, MEIKE · 2020 to 2022
$127k
NIGMS NIH HHS T32 GM007183NIH HHS P40 OD018537NINDS NIH HHS F31 NS120458NINDS NIH HHS K01 NS102342
6 · The paper itself

Abstract

Throughout the nervous system, the convergence of two or more presynaptic inputs on a target cell is commonly observed. The question we ask here is to what extent converging inputs influence each other's structural and functional synaptic plasticity. In complex circuits, isolating individual inputs is difficult because postsynaptic cells can receive thousands of inputs. An ideal model to address this question is the

Indexed as

AnimalsDrosophila melanogasterElectrophysiological PhenomenaExcitatory Postsynaptic PotentialsFemaleGene Knockout TechniquesLarvaMaleMotor NeuronsMusclesNeuromuscular JunctionNeuronal PlasticityReceptors, GlutamateSynapsesSynaptic TransmissionReceptors, Glutamateco-innervationcompensationneuromuscular junctionneurotransmissionplasticitysynaptic growth

Identifiers

PMID33402422
PMCPMC7896011
OpenAlexW3120029123

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.