Evidence map›Paper›PMID 33407219›Full record

SynthesisBMC geriatrics2021

Prevalence of mild cognitive impairment in community-dwelling Chinese populations aged over 55 years: a meta-analysis and systematic review.

Yuan Lu, Chaojie Liu, Dehua Yu, Sally Fawkes, Jia Ma, Min Zhang, Chunbo Li

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Prevalence of mild cognitive impairment in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Pooled it
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  7. Differential Improvement in Memory and Executive Functions: Personalized Exercise versus Acupuncture for Mild Cognitive Impairment in Stroke-prone Individuals.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Article
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  11. Effects of balance physical therapy with or without cognitive training in adults with cognitive and balance impairments : a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuan LuDepartment of General Practice, Yangpu hospital, Tongji University School of Medicine, Shanghai, 200090, China.
Chaojie LiuSchool of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia. c.liu@latrobe.edu.au.ORCID 0000-0003-0877-0424
Dehua YuDepartment of General Practice, Yangpu hospital, Tongji University School of Medicine, Shanghai, 200090, China. ydh1404@sina.com.
Sally FawkesSchool of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Jia MaAcademic Department of General Practice, Yangpu hospital, Tongji University School of Medicine, Shanghai, 200090, China.
Min ZhangAcademic Department of General Practice, Yangpu hospital, Tongji University School of Medicine, Shanghai, 200090, China.
Chunbo LiClinical Research Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shangha, China.

Funding

La Trobe University LTUFFRSShanghai Municipal Health Bureau 201940495
6 · The paper itself

Abstract

backgroundMild cognitive impairment (MCI) is an intermediate phase between normal cognitive ageing and overt dementia, with amnesic MCI (aMCI) being the dominant subtype. This study aims to synthesise the prevalence results of MCI and aMCI in community-dwelling populations in China through a meta-analysis and systematic review.

methodsThe study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol. English and Chinese studies published before 1 March 2020 were searched from ten electronic bibliographic databases. Two reviewers screened for relevance of the studies against the pre-defined inclusion and exclusion criteria and assessed the quality of the included studies using the Risk of Bias Tool independently. A random-effect model was adopted to estimate the prevalence of MCI and aMCI, followed by sub-group analyses and meta-regression. Sensitivity and publication bias tests were performed to verify the robustness of the meta-analyses.

resultsA total of 41 studies with 112,632 participants were included in the meta-analyses. The Chinese community-dwelling populations over 55 years old had a pooled prevalence of 12.2% [95% confidence interval (CI): 10.6, 14.2%] for MCI and 10.9% [95% CI, 7.7, 15.4%] for aMCI, respectively. The prevalence of MCI increased with age. The American Psychiatric Association's Diagnostic tool (DSM-IV) generated the highest MCI prevalence (13.5%), followed by the Petersen criteria (12.9%), and the National Institute on Aging Alzheimer's Association (NIA-AA) criteria (10.3%). Women, rural residents, and those who lived alone and had low levels of education had higher MCI prevalence than others.

conclusionHigher MCI prevalence was identified in community-dwelling older adult populations in China compared with some other countries, possibly due to more broadened criteria being adopted for confirming the diagnosis. The study shows that aMCI accounts for 66.5% of MCI, which is consistent with findings of studies undertaken elsewhere. SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO CRD42019134686.

Indexed as

Alzheimer DiseaseCognitive DysfunctionAgedChinaFemaleHumansIndependent LivingPrevalenceSensitivity and SpecificityMeta-analysisMild cognitive impairmentPrevalenceSystematic review

Identifiers

PMID33407219
PMCPMC7789349

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.