Evidence map›Paper›PMID 33409552›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2021

Vasopressin-stimulated ORAI1 expression and store-operated Ca

Xuexue Zhu, Ke Ma, Kuo Zhou, Jibin Liu, Bernd Nürnberg, Florian Lang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Alterations of the CaFrontiers in physiology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Xuexue ZhuDepartment of Pharmacology, Experimental Therapy & Toxicology, Eberhard-Karls-University of Tübingen, Tübingen, Germany.ORCID 0000-0002-4735-5648
Ke MaDepartment of Pharmacology, Experimental Therapy & Toxicology, Eberhard-Karls-University of Tübingen, Tübingen, Germany.
Kuo ZhouDepartment of Pharmacology, Experimental Therapy & Toxicology, Eberhard-Karls-University of Tübingen, Tübingen, Germany.
Jibin LiuInstitute of Preventive Veterinary Medicine, Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China.
Bernd NürnbergDepartment of Pharmacology, Experimental Therapy & Toxicology, Eberhard-Karls-University of Tübingen, Tübingen, Germany.
Florian LangDepartment of Cardiology and Cardiovascular Medicine, University Hospital of Tübingen, Tübingen, Germany. florian.lang@uni-tuebingen.de.ORCID 0000-0003-2962-1540
University of Tübingen · DESichuan Agricultural University · CNUniversity Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular calcification may result from stimulation of osteogenic signalling with upregulation of the transcription factors CBFA1, MSX2 and SOX9, as well as alkaline phosphatase (ALPL), which degrades and thus inactivates the calcification inhibitor pyrophosphate. Osteogenic signalling further involves upregulation of the Ca

Indexed as

AortaBenzoatesBridged Bicyclo Compounds, HeterocyclicCalcium Channel BlockersCalcium SignalingCells, CulturedDrug Evaluation, PreclinicalHumansImmediate-Early ProteinsMuscle, Smooth, VascularMyocytes, Smooth MuscleNeoplasm ProteinsNitrendipineORAI1 ProteinOsteogenesisProtein Serine-Threonine Kinases2-cyclopentyl-4-(5-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl)-benzoic acidBenzoatesBridged Bicyclo Compounds, HeterocyclicCalcium Channel BlockersImmediate-Early ProteinsMRS 1845Neoplasm ProteinsNitrendipineORAI1 ProteinORAI1 protein, humanProtein Serine-Threonine KinasesSerum-Glucocorticoid Regulated KinasesSTIM1 protein, humanStromal Interaction Molecule 1VasopressinsAlkaline phosphataseHAoSMCsORAI1Osteogenic signallingSTIM1Store-operated Ca2+ entry

Identifiers

PMID33409552
OpenAlexW3120093320

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.