Evidence map›Paper›PMID 33410377›Full record

ArticleCell cycle (Georgetown, Tex.)2021

Silenced lncRNA H19 and up-regulated microRNA-129 accelerates viability and restrains apoptosis of PC12 cells induced by Aβ

Yan-Yun Zhang, Hai-Lan Bao, Li-Xia Dong, Yu Liu, Guo-Wei Zhang, Feng-Mao An

Abstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan-Yun ZhangCollege of Nursing, Inner Mongolia University for Nationalities , Tongliao, P.R. China.
Hai-Lan BaoCollege of Nursing, Inner Mongolia University for Nationalities , Tongliao, P.R. China.
Li-Xia DongCollege of Nursing, Inner Mongolia University for Nationalities , Tongliao, P.R. China.
Yu LiuCollege of Nursing, Inner Mongolia University for Nationalities , Tongliao, P.R. China.
Guo-Wei ZhangCollege of Nursing, Inner Mongolia University for Nationalities , Tongliao, P.R. China.
Feng-Mao AnInstitute of Dementia, Inner Mongolia University for Nationalities , Tongliao, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating data manifest that long non-coding RNA (lncRNAs) are involved in all kinds of neurodegenerative disorders, consisting of the onset and progression of Alzheimer's disease (AD). The study was for the research of the mechanism of lncRNA H19 (H19) in viability and apoptosis of PC12 cells induced by Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisCell Line, TumorCell SurvivalHMGB1 ProteinMembrane Potential, MitochondrialMicroRNAsNeuronsOxidative StressPC12 CellsPeptide FragmentsRatsRNA, Long NoncodingSignal TransductionAmyloid beta-PeptidesH19 long non-coding RNAHMGB1 ProteinMicroRNAsMIRN129 microRNA, ratPeptide FragmentsRNA, Long NoncodingAlzheimer’s diseaseapoptosisAβ25-35high mobility group box-1 proteinlong non-coding RNA H19MicroRNA-129PC12 cellsviability

Identifiers

PMID33410377
PMCPMC7849745

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.