Evidence map›Paper›PMID 33411068›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

24-hour ambulatory blood pressure monitoring 9 years after pediatric cardiac surgery: a pilot and feasibility study.

Daniel Fredric, Jason H Greenberg, Chirag R Parikh, Prasad Devarajan, Hayton Chui, Vedran Cockovski, Michael Pizzi, Ana Palijan, Erin Hessey, Yaqi Jia and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Daniel FredricDepartment of Pediatrics, Division of Nephrology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, 686 Bay Street, 11th floor, Room 11.9722, Toronto, ON, M5G 0A4, Canada.
Jason H GreenbergSection of Nephrology, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.
Chirag R ParikhDivision of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Prasad DevarajanDepartment of Nephrology and Hypertension, Cincinnati Children's Hospital, University of Cincinnati, Cincinnati, OH, USA.
Hayton ChuiDepartment of Pediatrics, Division of Nephrology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, 686 Bay Street, 11th floor, Room 11.9722, Toronto, ON, M5G 0A4, Canada.
Vedran CockovskiDepartment of Pediatrics, Division of Nephrology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, 686 Bay Street, 11th floor, Room 11.9722, Toronto, ON, M5G 0A4, Canada.
Michael PizziMcGill University Health Centre Research Institute, Montreal, QC, Canada.
Ana PalijanMcGill University Health Centre Research Institute, Montreal, QC, Canada.
Erin HesseyFaculty of Medicine, University of Alberta, Edmonton, AB, Canada.
Yaqi JiaDivision of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Heather R Thiessen-PhilbrookDivision of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Michael ZappitelliDepartment of Pediatrics, Division of Nephrology, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, 686 Bay Street, 11th floor, Room 11.9722, Toronto, ON, M5G 0A4, Canada. michael.zappitelli@sickkids.ca.
Hospital for Sick Children · CAMcGill University Health Centre · CAJohns Hopkins University · USCincinnati Children's Hospital Medical Center · USJohns Hopkins Medicine · USUniversity of Alberta · CAYale University · US

Funding

Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney InjuryR01HL085757 · NHLBI · YALE UNIVERSITY · PI PARIKH, CHIRAG R · 2007 to 2019
$10.3M
Proteomics CoreP50DK096418 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI DEVARAJAN, PRASAD · 2012 to 2021
$8.4M
Progression of Acute Kidney Injury to Chronic Kidney DiseaseU01DK082185 · NIDDK · YALE UNIVERSITY · PI PARIKH, CHIRAG R · 2008 to 2017
$5.1M
Novel Biomarkers of Chronic Kidney Disease in ChildrenK08DK110536 · NIDDK · YALE UNIVERSITY · PI GREENBERG, JASON HENRY · 2016 to 2021
$882k
NHLBI NIH HHS R01 HL085757NIDDK NIH HHS K08 DK110536NIDDK NIH HHS P50 DK096418NIDDK NIH HHS U01 DK082185
6 · The paper itself

Abstract

backgroundChildren undergoing cardiac surgery are at risk of high blood pressure (BP), a risk factor for cardiovascular and kidney disease. Twenty-four-hour ambulatory BP monitoring (ABPM) is a reference standard hypertension (HTN) test. Little data exist on ABPM abnormalities in children several years post cardiac surgery. This study aimed to (a) determine ABPM feasibility; (b) describe and compare ABPM measures and abnormalities (percent load, masked HTN [MH]; non-dipping, mean systolic/diastolic BP > 95th percentile; pre-HTN (ABPM); white-coat HTN [WCH]) to casual BP; and (c) compare BP in patients with and without acute kidney injury (AKI).

methodsProspective, follow-up pilot study of children (0-18 years) who underwent cardiac surgery from 2007 to 2009 at Montreal Children's Hospital. We recorded if participants had post-operative AKI and assessed the following outcomes at 9-year follow-up: casual BP classified by three single-visit measures (normal; elevated BP [eBP

resultsTwenty-three patients (median [interquartile range], 8.6 [8.0, 9.0] years post cardiac surgery) were included; 16 (70%) male. Six participants (26%) had eBP

conclusionOur pilot study determined that ABPM was feasible in children years after cardiac surgery and frequently identified ABPM abnormalities. Future research in larger populations is needed to define specific risk factors for HTN in children after cardiac surgery.

Indexed as

Acute Kidney InjuryBlood Pressure Monitoring, AmbulatoryCardiac Surgical ProceduresHypertensionChildFeasibility StudiesFemaleHumansMalePilot ProjectsProspective StudiesAmbulatory blood pressure monitoringBlood pressureCardiac surgeryChildrenHypertension

Identifiers

PMID33411068
PMCPMC10942669
OpenAlexW3120304166

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.