ArticlePediatric nephrology (Berlin, Germany)2021
Isolated nocturnal hypertension is associated with increased left ventricular mass index in children.
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Pulse wave velocity in high-risk pregnant women who subsequently developed early- and late-onset preeclampsia.Journal of human hypertension · 2026Article
- Pediatric Ambulatory Blood Pressure Patterns and Cardiovascular Risk.Current hypertension reports · 2026Review
- The correlation between insulin-like growth factor 1 and left ventricular mass index in obese children.BMC endocrine disorders · 2025Article
- Measurement of Blood Pressure in Children and Adolescents Outside the Office for the Diagnosis of Hypertension.Current cardiology reports · 2025Review
- Prospective Study of Modifiable Risk Factors of Arterial Hypertension and Left Ventricular Hypertrophy in Pediatric Patients on Hemodialysis.Kidney international reports · 2024Article
- Treatment of Hypertension in Children.Current hypertension reviews · 2024Review
- Masked Hypertension in Healthy Children and Adolescents: Who Should Be Screened?Current hypertension reports · 2023Review
- Nocturnal Hypertension in Children With Chronic Kidney Disease Is Common and Associated With Progression to Kidney Replacement Therapy.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Isolated nocturnal hypertension in relation to host and environmental factors and clock genes.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Isolated Nocturnal Hypertension in Children.Frontiers in pediatrics · 2022Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIsolated nocturnal hypertension (INH) is associated with increased prevalence of left ventricular hypertrophy (LVH) and cardiovascular morbidity and mortality in adult patients. Unlike in adults, data illustrating the possible association between INH and cardiac target organ damage is lacking in children. This study aimed to investigate whether INH is associated with increased left ventricular mass index (LVMI) and LVH in children.
methodsRetrospective data from all untreated children with confirmed ambulatory hypertension (HT) in our center was reviewed. Ambulatory blood pressure monitoring (ABPM) and echocardiography were performed concurrently. Ambulatory normotensive children served as controls. LVH was defined as LVMI ≥ 95th percentile.
resultsThere were 102 ABPM studies; of these, 79 children had renal HT, and 23 had primary HT. Median age of children was 13.2 years (3.8-18.9). Nineteen children had INH, 9 children had isolated daytime HT, 54 had daytime and nighttime HT, and 20 were normotensive. The LVMI adjusted for age (patient's LVMI/95th percentile of the LVMI) was significantly higher in children with INH than in normotensive children (0.83 ± 0.03 vs. 0.74 ± 0.03, p = 0.03). Left ventricular hypertrophy was present in 11% of children with INH; this was not significantly higher than in normotensive children (0%, p = 0.23).
conclusionsThis study investigated the association between INH and cardiac structure in children with primary and renal HT and showed children with INH had higher LVMI adjusted for age than normotensive children and children with INH had similar LVMI adjusted for age to children with isolated daytime HT.
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