Evidence map›Paper›PMID 33414130›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2021

Knockout of

Letao Fan, Wenjun Gao, Yedan Liu, Joshua R Jefferson, Fan Fan, Richard J Roman

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Letao FanDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0001-5328-8050
Wenjun GaoDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Yedan LiuDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Joshua R JeffersonDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Fan FanDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Richard J RomanDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi rroman@umc.edu.
University of Mississippi Medical Center · US

Funding

The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
Cerebrovascular resistance in cognitive aging and Alzheimer's disease riskR01AG060049 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NATION, DANIEL A · 2020 to 2023
$2.4M
Genetic determinants of hypertension-induced cerebral vascular dysfunctionR01HL138685 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROMAN, RICHARD J. · 2018 to 2021
$1.9M
Adducin, actin cytoskeleton and cognitive impairmentsR01AG057842 · NIA · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2019 to 2023
$1.9M
Renal microcirculation and hypertension induced renal injuryR01DK104184 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROMAN, RICHARD J. · 2014 to 2017
$1.8M
NHLBI NIH HHS R01 HL138685NIA NIH HHS R01 AG057842NIA NIH HHS R01 AG060049NIDDK NIH HHS R01 DK104184NIGMS NIH HHS P20 GM104357
6 · The paper itself

Abstract

Previous studies identified a region on chromosome 1 associated with N

Indexed as

AdducinsAnimalsBlood PressureCalmodulin-Binding ProteinsEnzyme InhibitorsGene DeletionGlomerular Filtration RateHomeostasisHypertension, RenalMaleNG-Nitroarginine Methyl EsterPodocytesRatsRenal CirculationRenal Insufficiency, ChronicVasoconstrictionAdd3 protein, ratAdducinsCalmodulin-Binding ProteinsEnzyme InhibitorsNG-Nitroarginine Methyl Ester

Identifiers

PMID33414130
PMCPMC8051517
OpenAlexW3119619107

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.