Evidence map›Paper›PMID 33424724›Full record

ReviewFrontiers in psychology2020

Effects of Neurological Disorders on Bone Health.

Ryan R Kelly, Sara J Sidles, Amanda C LaRue

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
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  10. Targeting TMEM175 in Lysosomal Physiology and Human Diseases.Current stem cell research & therapy · 2026
    Review
  11. Article
  12. Article
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  15. Article
  16. Bone biomarkers in post-polio clinic patients.Frontiers in endocrinology · 2025
    Article
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ryan R KellyResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States.
Sara J SidlesResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States.
Amanda C LaRueResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States.
Medical University of South Carolina · USRalph H. Johnson VA Medical Center · US

Funding

Potential of Hematopoietic Stem Cell-Based Therapies for Complicated FracturesI01BX000333 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI LARUE, AMANDA C. · 2009 to 2022
–
BLRD VA I01 BX000333
6 · The paper itself

Abstract

Neurological diseases, particularly in the context of aging, have serious impacts on quality of life and can negatively affect bone health. The brain-bone axis is critically important for skeletal metabolism, sensory innervation, and endocrine cross-talk between these organs. This review discusses current evidence for the cellular and molecular mechanisms by which various neurological disease categories, including autoimmune, developmental, dementia-related, movement, neuromuscular, stroke, trauma, and psychological, impart changes in bone homeostasis and mass, as well as fracture risk. Likewise, how bone may affect neurological function is discussed. Gaining a better understanding of brain-bone interactions, particularly in patients with underlying neurological disorders, may lead to development of novel therapies and discovery of shared risk factors, as well as highlight the need for broad, whole-health clinical approaches toward treatment.

Indexed as

bonedepressiondiseasemental healthNeurologyosteoporosisPTSD

Identifiers

PMID33424724
PMCPMC7793932
OpenAlexW3109855341

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.