ReviewFrontiers in bioengineering and biotechnology2020
Biomaterials in Valvular Heart Diseases.
Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review).International journal of molecular medicine · 2026Review
- Nanoparticle Biofunctionalization of Bioprosthetic Heart Valves to Modulate Mechanisms of Structural Valve Deterioration.JACC. Basic to translational science · 2026Article
- Assessment of Prevalence and Characteristics of Valvular Heart Disease: A Cross-Sectional Study From Yazd Health Study.Health science reports · 2026Article
- Impact of leaflet stiffness in aortic valve neocuspidization in ex vivo biomechanical simulation.JTCVS open · 2026Article
- The use of transgenic animals for xenotransplantation: An update.Animal models and experimental medicine · 2025Review
- Implant Infectious Diseases: An Introduction to Biomaterials for ID Physicians.Open forum infectious diseases · 2025Review
- Full-Field Assessment of Geometry and Collagenous Architecture of Porcine Valve Leaflets via Laser Micrometry and Quantitative Polarized Light Imaging.Journal of biophotonics · 2025Article
- Mechanistic Insights into Bioprosthetic Heart Valve Calcification and Anti-Calcification Strategies.Reviews in cardiovascular medicine · 2025Review
- Longevity mechanisms in cardiac aging: exploring calcium dysregulation and senescence.Biogerontology · 2025Review
- Association between clinician team segregation, receipt of cardiovascular care and outcomes in valvular heart diseases.ESC heart failure · 2025Article
- Stuck Prosthetic Valves: Clinical Implications of Pannus Formation and Gradient Measurement in Surgical Outcomes.Journal of clinical medicine · 2025Article
- Natural biomaterials in the management of the aortic valve pathology. Biomedical and clinical aspects: A review.Biomolecules & biomedicine · 2025Review
- Trends in complications of cardiac and vascular prosthetic devices, implants, and grafts mortality rate in the United States (1999-2020).Annals of medicine and surgery (2012) · 2025Review
- The Bidirectional Relationship Between Cardiovascular Medications and Oral and Gut Microbiome Health: A Comprehensive Review.Microorganisms · 2024Review
- Review
- Recent progress in functional modification and crosslinking of bioprosthetic heart valves.Regenerative biomaterials · 2024Review
- Fibrin gel enhanced trilayer structure in cell-cultured constructs.Biotechnology and bioengineering · 2023Article
- Growing Heart Valve Implants for Children.Journal of cardiovascular development and disease · 2023Review
- Perfluorocarbons: A perspective of theranostic applications and challenges.Frontiers in bioengineering and biotechnology · 2023Review
- Electrically conductive carbon-based (bio)-nanomaterials for cardiac tissue engineering.Bioengineering & translational medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Valvular heart disease (VHD) occurs as the result of valvular malfunction, which can greatly reduce patient's quality of life and if left untreated may lead to death. Different treatment regiments are available for management of this defect, which can be helpful in reducing the symptoms. The global commitment to reduce VHD-related mortality rates has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches have dramatically improved the quality of life for VHD patients, yet the search for low cost, more effective, and less invasive approaches is ongoing. The gold standard approach for VHD management is to replace or repair the injured valvular tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac valve regeneration and repair holds a great promise for treatment of this type of heart disease. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.