Evidence map›Paper›PMID 33425878›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs.

Tanja Niedermair, Christoph Lukas, Shushan Li, Sabine Stöckl, Benjamin Craiovan, Christoph Brochhausen, Marianne Federlin, Marietta Herrmann, Susanne Grässel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Exosomes promise better bone regeneration.Regenerative therapy · 2025
    Review
  6. Article
  7. Review
  8. Extracellular vesicles in bone aging: therapeutic strategies and applications.Extracellular vesicles and circulating nucleic acids · 2025
    Review
  9. Review
  10. Review
  11. The Potential of Exosomes for Osteoporosis Treatment: A Review.Drug design, development and therapy · 2024
    Review
  12. Delivery of Growth Factors to Enhance Bone Repair.Bioengineering (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Total Flavonoids fromCombinatorial chemistry & high throughput screening · 2023
    Article
  15. Article
  16. Effects of Loganin on Bone Formation and Resorption In Vitro and In Vivo.International journal of molecular sciences · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tanja NiedermairInstitute of Pathology, University of Regensburg, Regensburg, Germany.
Christoph LukasDepartment of Orthopaedic Surgery, Experimental Orthopaedics, Centre for Medical Biotechnology (ZMB/Biopark 1), University of Regensburg, Regensburg, Germany.
Shushan LiDepartment of Orthopaedic Surgery, Experimental Orthopaedics, Centre for Medical Biotechnology (ZMB/Biopark 1), University of Regensburg, Regensburg, Germany.
Sabine StöcklDepartment of Orthopaedic Surgery, Experimental Orthopaedics, Centre for Medical Biotechnology (ZMB/Biopark 1), University of Regensburg, Regensburg, Germany.
Benjamin CraiovanChair of Arthroplasty, Center for Orthopaedics and Trauma Surgery, University Hospital Giessen and Marburg GmbH, Marburg, Germany.
Christoph BrochhausenInstitute of Pathology, University of Regensburg, Regensburg, Germany.
Marianne FederlinDepartment of Conservative Dentistry and Periodontology, University Medical Center Regensburg, Regensburg, Germany.
Marietta HerrmannIInterdisciplinary Center for Clinical Research (IZKF), Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Wuerzburg and Bernhard-Heine-Center for Locomotion Research, University of Würzburg, Würzburg, Germany.
Susanne GrässelDepartment of Orthopaedic Surgery, Experimental Orthopaedics, Centre for Medical Biotechnology (ZMB/Biopark 1), University of Regensburg, Regensburg, Germany.
University of Regensburg · DEUniversitätsklinikum Gießen und Marburg · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EVsextracellular vesiclesmesenchymal stem cellsosteoarthritisosteoblastsosteogenic differentiationosteoporosis

Identifiers

PMID33425878
PMCPMC7785908
OpenAlexW3114400770

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.