ArticlePhysiological reports2021
Muscle blood flow is independent of conduit artery diameter following prior vasodilation in males.
Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Interaction of sublingual glyceryl tri-nitrate administration on single muscle contraction-induced hyperemia: potential insight into the role of the skeletal muscle pump.Frontiers in physiology · 2026Article
- Muscle blood flow is independent of conduit artery diameter following prior vasodilation in males.Physiological reports · 2021Article
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4 authors at 4 institutions in 1 country.
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Abstract
At the onset of exercise in humans, muscle blood flow (MBF) increases to a new steady-state that closely matches the metabolic demand of exercise. This increase has been attributed to "contraction-induced vasodilation," comprised of the skeletal muscle pump and rapid vasodilatory mechanisms. While most research in this area has focused on forearm blood flow (FBF) and vascular conductance, it is possible that separating FBF into diameter and blood velocity can provide more useful information on MBF regulation downstream of the conduit artery. Therefore, we attempted to dissociate the matching of oxygen delivery and oxygen demand by administering glyceryl tri-nitrate (GTN) prior to handgrip exercise. Eight healthy males (29 ± 9 years) performed two trials consisting of two bouts of rhythmic handgrip exercise (30 contractions·min
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