Evidence map›Paper›PMID 33428246›Full record

ArticleThe EMBO journal2021

Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.

Lina Worpenberg, Chiara Paolantoni, Sara Longhi, Miriam M Mulorz, Tina Lence, Hans-Hermann Wessels, Erik Dassi, Giuseppe Aiello, F X Reymond Sutandy, Marion Scheibe and 12 more

Open access · greenAbstract read
In one paragraph

Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 86 citations in OpenAlex.

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  15. Decoding Nucleotide Repeat Expansion Diseases: Novel Insights fromInternational journal of molecular sciences · 2024
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  17. Insights into the role of RNA mGenes & diseases · 2024
    Review
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  20. RNA modifications in insects.Frontiers in insect science · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 4 countries.

Lina WorpenbergCenter for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Chiara PaolantoniCenter for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Sara LonghiLaboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Miriam M MulorzInstitute of Molecular Biology (IMB), Mainz, Germany.
Tina LenceInstitute of Molecular Biology (IMB), Mainz, Germany.ORCID 0000-0001-9377-546X
Hans-Hermann WesselsMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.ORCID 0000-0001-5551-404X
Erik DassiLaboratory of RNA Regulatory Networks, Department CIBIO, University of Trento, Trento, Italy.
Giuseppe AielloArmenise-Harvard Laboratory of Brain Disorders and Cancer, Department CIBIO, University of Trento, Trento, Italy.ORCID 0000-0001-8723-2127
F X Reymond SutandyInstitute of Molecular Biology (IMB), Mainz, Germany.
Marion ScheibeInstitute of Molecular Biology (IMB), Mainz, Germany.
Raghu R EdupugantiDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Anke BuschBioinformatics Core Facility, IMB, Mainz, Germany.
Martin M MöckelProtein Production Core Facility, IMB, Mainz, Germany.
Michiel VermeulenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.ORCID 0000-0003-0836-6894
Falk ButterInstitute of Molecular Biology (IMB), Mainz, Germany.ORCID 0000-0002-7197-7279
Julian KönigInstitute of Molecular Biology (IMB), Mainz, Germany.
Michela NotarangeloLaboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Uwe OhlerMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.ORCID 0000-0002-0881-3116
Christoph DieterichKlaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0001-9468-6311
Alessandro QuattroneCenter for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-3333-7630
Alessia SoldanoLaboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.ORCID 0000-0002-3120-9929
Jean-Yves RoignantCenter for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-1395-2150
Institute of Molecular Biology · DEUniversity of Trento · ITMax Delbrück Center · DERadboud University Nijmegen · NLUniversity of Lausanne · CHHeidelberg University · DEJohannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenosine (m

Indexed as

AdenosineAnimalsAxonsDrosophila melanogasterDrosophila ProteinsFragile X Messenger Ribonucleoprotein 1NeuronsRNA-Binding ProteinsRNA, MessengerAdenosineDrosophila ProteinsFMR1 protein, DrosophilaFragile X Messenger Ribonucleoprotein 1N-methyladenosineRNA-Binding ProteinsRNA, MessengerFmr1m6Anervous systemRNA modificationYthdf

Identifiers

PMID33428246
PMCPMC7883056
OpenAlexW3119069404

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.