Evidence map›Paper›PMID 33430262›Full record

ArticlePolymers2021

Biocompatible Lipid Polymer Cationic Nanoparticles for Antigen Presentation.

Yunys Pérez-Betancourt, Bianca de Carvalho Lins Fernandes Távora, Eliana L Faquim-Mauro, Ana Maria Carmona-Ribeiro

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Emerging Cationic Nanovaccines.Pharmaceutics · 2024
    Review
  4. Review
  5. Article
  6. Supramolecular Nanostructures for Vaccines.Biomimetics (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Antimicrobial Polymer-Based Assemblies: A Review.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yunys Pérez-BetancourtBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Avenida Professor Lineu Prestes, 748 Butantan, São Paulo CEP 05508-000, Brazil.ORCID 0000-0003-4998-5173
Bianca de Carvalho Lins Fernandes TávoraImmunopathology Laboratory, Butantan Institute, Av. Vital Brasil, 1500 Butantan, São Paulo 05503-900, Brazil.
Eliana L Faquim-MauroImmunopathology Laboratory, Butantan Institute, Av. Vital Brasil, 1500 Butantan, São Paulo 05503-900, Brazil.
Ana Maria Carmona-RibeiroBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Avenida Professor Lineu Prestes, 748 Butantan, São Paulo CEP 05508-000, Brazil.ORCID 0000-0001-8500-2707
Instituto Butantan · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302352/2014-7Conselho Nacional de Desenvolvimento Científico e Tecnológico 302758/2019-4Conselho Nacional de Desenvolvimento Científico e Tecnológico 312096/2018-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/17685-2
6 · The paper itself

Abstract

Biocompatible lipid polymer nanoparticles (NPs) previously used as antimicrobial agents are explored here as immuno-adjuvants. Poly (methyl methacrylate) (PMMA)/dioctadecyldimethylammonium bromide (DODAB)/poly (diallyldimethylammonium chloride) (PDDA) nanoparticles (NPs) were prepared by emulsion polymerization of methyl methacrylate (MMA) in the presence of DODAB and PDDA, with azobisisobutyronitrile (AIBN) as the initiator. NPs characterization after dialysis by dynamic light-scattering yielded 225 ± 2 nm hydrodynamic diameter (Dz), 73 ± 1 mV zeta-potential (

Indexed as

biocompatible polymercationic lipidcationic nanoparticles toxicitycationic polymerhumoral and cellular immune responseshybrid nanoparticlesovalbuminprotein deliveryvaccine adjuvants

Identifiers

PMID33430262
PMCPMC7825723
OpenAlexW3118809293

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.