Evidence map›Paper›PMID 33430357›Full record

ReviewJournal of clinical medicine2021

Acute Pancreatitis: Genetic Risk and Clinical Implications.

Frank U Weiss, Felix Laemmerhirt, Markus M Lerch

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. The Diagnostic Value of Procalcitonin in Patients with Severe Acute Pancreatitis: A Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in genetics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The role of biomarkers in the early diagnosis of acute kidney injury associated with acute pancreatitis: Evidence from 582 cases.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  16. Association Between Ascites and Clinical Findings in Patients with Acute Pancreatitis: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Frank U WeissDepartment of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0003-3369-6369
Felix LaemmerhirtDepartment of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.
Markus M LerchDepartment of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.
Universitätsmedizin Greifswald · DE

Funding

Deutsche Forschungsgemeinschaft GRK 1947/A3European Union V-630-S150-2012/132/133, ESF/14-BM-A55-0045/16, TBI-V-242-VBW-084, TBI-V-1-245-VBW-085Federal Ministry of Education and Research BMBF GANI-MED 03IS2061A, 0314107, 01ZZ9603, 01ZZ0103, 01ZZ0403, 03ZIK012, FKZ: 01EK1511AMildred-Scheel-Stiftung 109102
6 · The paper itself

Abstract

Acute pancreatitis (AP) is one of the most common gastroenterological indications for emergency admittance and hospitalization. Gallstones, alcohol consumption or the presence of additional initiating factors give rise to a disease with a diverse clinical appearance and a hard-to predict course of progression. One major challenge in the treatment of AP patients is the early identification of patients at risk for the development of systemic complications and organ failure. In addition, 20%-30% of patients with a first episode of AP later experience progress to recurrent or chronic disease. Complex gene-environment interactions have been identified to play a role in the pathogenesis of pancreatitis, but so far no predictive genetic biomarkers could be implemented into the routine clinical care of AP patients. The current review explains common and rare etiologies of acute pancreatitis with emphasis on underlying genetic aberrations and ensuing clinical management.

Indexed as

acute pancreatitisdiagnosisdisease severitygenetic riskprogression

Identifiers

PMID33430357
PMCPMC7825757
OpenAlexW3120202688

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.