Evidence mapPaperPMID 33433751Full record

ArticleGeroScience2021

Exogenous hydrogen sulfide and miR-21 antagonism attenuates macrophage-mediated inflammation in ischemia reperfusion injury of the aged kidney.

Sathnur Pushpakumar, Sourav Kundu, Gregory Weber, Utpal Sen

Open access · greenAbstract read
In one paragraph

Article in GeroScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Deciphering the impact ofGenes & diseases · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. miRNA in the Progression of Diabetic Kidney Disease: New Insight.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sathnur PushpakumarDepartment of Physiology, University of Louisville School of Medicine, 500 S Preston St. HSC-A, Room 1115, Louisville, KY, 40202, USA. sbpush01@louisville.edu.ORCID https://orcid.org/0000-0002-5984-166X
Sourav KunduNMCG Laboratory ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata, West Bengal, 700120, India.
Gregory WeberDepartment of Physiology, University of Louisville School of Medicine, 500 S Preston St. HSC-A, Room 1115, Louisville, KY, 40202, USA.
Utpal SenDepartment of Physiology, University of Louisville School of Medicine, 500 S Preston St. HSC-A, Room 1115, Louisville, KY, 40202, USA. utpal.sen@louisville.edu.
University of Louisville · USCentral Inland Fisheries Research Institute · IN

Funding

miRNA Mechanism of Acute Kidney Injury in AgingR01DK116591 · NIDDK · UNIVERSITY OF LOUISVILLE · PI Utpal Sen, Suresh C. Tyagi · 2021 to 2021
$545k
NIDDK NIH HHS R01 DK116591
6 · The paper itself

Abstract

Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in the aging population. A reduction of hydrogen sulfide (H

Indexed as

Hydrogen SulfideInflammationKidneyMacrophagesMicroRNAsReperfusion InjuryAnimalsCystathionine gamma-LyaseEndothelial CellsMiceMice, Inbred C57BLCystathionine gamma-LyaseHydrogen SulfideMicroRNAsMIRN21 microRNA, mouseHydrogen sulfideIRIMacrophage polarizationMicroRNA-21

Identifiers

PMID33433751
PMCPMC8190249
OpenAlexW3120972620

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.