Evidence map›Paper›PMID 33435130›Full record

ArticleInternational journal of molecular sciences2021

Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy.

Juan Carlos Gil-Redondo, Jagoba Iturri, Felipe Ortega, Raquel Pérez-Sen, Andreas Weber, María Teresa Miras-Portugal, José Luis Toca-Herrera, Esmerilda G Delicado

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Dissecting the Purinergic Signaling Puzzle.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Juan Carlos Gil-RedondoDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.ORCID 0000-0002-4797-7033
Jagoba IturriDepartment of Nanobiotechnology (DNBT), Institute for Biophysics, BOKU University for Natural Resources and Life Sciences, Muthgasse 11 (Simon Zeisel Haus), A-1190 Vienna, Austria.ORCID 0000-0001-7392-5352
Felipe OrtegaDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6398-9520
Raquel Pérez-SenDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.
Andreas WeberDepartment of Nanobiotechnology (DNBT), Institute for Biophysics, BOKU University for Natural Resources and Life Sciences, Muthgasse 11 (Simon Zeisel Haus), A-1190 Vienna, Austria.ORCID 0000-0001-6462-7687
María Teresa Miras-PortugalDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.
José Luis Toca-HerreraDepartment of Nanobiotechnology (DNBT), Institute for Biophysics, BOKU University for Natural Resources and Life Sciences, Muthgasse 11 (Simon Zeisel Haus), A-1190 Vienna, Austria.ORCID 0000-0001-8951-2616
Esmerilda G DelicadoDepartamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Instituto Universitario de Investigación en Neuroquímica (IUIN), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdiSSC), Universidad Complutense Madrid, 28040 Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESBOKU University · AT

Funding

Austrian Science Fund 29562-N62Comunidad de Madrid PR65/19-22453Ministerio de Ciencia, Innovación y Universidades BES-2015-071403Ministerio de Ciencia, Innovación y Universidades PID2019-109155RB-I00
6 · The paper itself

Abstract

Endothelial cells and astrocytes preferentially express metabotropic P2Y nucleotide receptors, which are involved in the maintenance of vascular and neural function. Among these, P2Y

Indexed as

Adenosine DiphosphateAstrocytesHumansHuman Umbilical Vein Endothelial CellsMicroscopy, Atomic ForceReceptors, Purinergic P2Receptors, Purinergic P2Y1Signal TransductionThionucleotidesUridine TriphosphateAdenosine Diphosphatemethylthio-ADPP2RY13 protein, humanReceptors, Purinergic P2Receptors, Purinergic P2Y1ThionucleotidesUridine Triphosphateastrocytesatomic force microscopyendothelial cellsnucleotide receptorP2Y nucleotide receptor

Identifiers

PMID33435130
PMCPMC7827192
OpenAlexW3120603606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.