Evidence map›Paper›PMID 33435565›Full record

ArticleMetabolites2021

Molecular Differences Based on Erythrocyte Fatty Acid Profile to Personalize Dietary Strategies between Adults and Children with Obesity.

Iker Jauregibeitia, Kevin Portune, Sonia Gaztambide, Itxaso Rica, Itziar Tueros, Olaia Velasco, Gema Grau, Alicia Martín, Luis Castaño, Anna Vita Larocca and 3 more

Abstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Iker JauregibeitiaAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio-Bizkaia, Spain.ORCID 0000-0002-3334-3099
Kevin PortuneAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio-Bizkaia, Spain.
Sonia GaztambideBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Itxaso RicaBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Itziar TuerosAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio-Bizkaia, Spain.ORCID 0000-0002-7609-5435
Olaia VelascoBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Gema GrauBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Alicia MartínBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Luis CastañoBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, Endo-ERN, 48903 Barakaldo, Spain.
Anna Vita LaroccaLipidomic Laboratory, Lipinutragen srl, Via di Corticella 181/4, 40128 Bologna, Italy.
Federica Di NolfoLipidomic Laboratory, Lipinutragen srl, Via di Corticella 181/4, 40128 Bologna, Italy.
Carla FerreriConsiglio Nazionale delle Ricerche, ISOF, Via Piero Gobetti 101, 40129 Bologna, Italy.ORCID 0000-0002-1359-0869
Sara ArranzAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio-Bizkaia, Spain.ORCID 0000-0002-0411-9784

Funding

ALTERNATIVE PATHWAYS OF T CELL ACTIVATIONK08AR002017 · NIAMS · VANDERBILT UNIVERSITY · PI BYRD, VICTOR M · 1998 to 2002
$348k
Agriculture and Fisheries of the Basque Country Government EMOI project funding by ELKARTEK 2017; Innovation Fund 2017Department of Health of the Basque Government 2017222033: OBESIA 2016-2019Fundación Gangoiti Fellowship 2018/19 y 2019/2020the Centre for the Development of Industrial Technology (CDTI) of the Spanish Ministry of Science and Innovation TECNOMIFOOD project (CER-20191010)the INC (INTERNATIONAL NUT AND DRIED FRUIT COUNCIL) OBINUT project (2016(II)-R01)
6 · The paper itself

Abstract

As the obesity epidemic continues to grow inexorably worldwide, the need to develop effective strategies to prevent and control obesity seems crucial. The use of molecular tools can be useful to characterize different obesity phenotypes to provide more precise nutritional recommendations. This study aimed to determine the fatty acid (FA) profile of red blood cell (RBC) membranes, together with the evaluation of their dietary intake and biochemical parameters, of children and adults with obesity. An observational study was carried out on 196 children (113 with normal weight and 83 with obesity) and 91 adults (30 with normal weight and 61 with obesity). Mature RBC membrane phospholipids were analyzed for FA composition by gas chromatography-mass spectrometry (GC-MS). Dietary habits were evaluated using validated food frequency questionnaires (FFQ). Children with obesity presented higher levels of ω-6 polyunsaturated FAs (mainly linoleic acid,

Indexed as

lipid metabolismmature erythrocyteobesityprecision nutrition

Identifiers

PMID33435565
PMCPMC7827034

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.