Evidence map›Paper›PMID 33439332›Full record

SynthesisEuropean journal of nutrition2021

Potential effect of tropical fruits Phyllanthus emblica L. for the prevention and management of type 2 diabetic complications: a systematic review of recent advances.

Hao-Zhou Huang, Min Qiu, Jun-Zhi Lin, Meng-Qi Li, Xi-Tao Ma, Fei Ran, Chuan-Hong Luo, Xi-Chuan Wei, Run-Chun Xu, Peng Tan and 4 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. LcSAO1, an Unconventional DOXB Clade 2OGD Enzyme fromInternational journal of molecular sciences · 2023
    Article
  7. Chinese herbal medicines · 2023
    Review
  8. Review
  9. Article
  10. Phytochemical Analysis and Antioxidant and Antidiabetic Activities of Extracts fromAdvances in pharmacological and pharmaceutical sciences · 2022
    Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Hao-Zhou Huang *Pharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.ORCID http://orcid.org/0000-0003-4245-3078
Min Qiu *Pharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.
Jun-Zhi LinTeaching Hospital of Chengdu University of TCM, Chengdu, 610072, China.
Meng-Qi LiSichuan Nursing Vocational College, Chengdu, 610100, China.
Xi-Tao MaTeaching Hospital of Chengdu University of TCM, Chengdu, 610072, China.
Fei RanPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.
Chuan-Hong LuoPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.
Xi-Chuan WeiPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.
Run-Chun XuPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China.
Peng TanState Key Laboratory of Biological Evaluation of Traditional Chinese Medicine Quality, National Administration of TCM, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 610041, China.
San-Hu FanSanajon Pharmaceutical Group, Chengdu, 610000, China.
Ming YangJiangxi University of Traditional Chinese Medicine, Nanchang, 330004, People's Republic of China.
Li HanPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China. hanliyx@163.com.
Ding-Kun ZhangPharmacy College, State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of TCM, Chengdu, 611137, China. zhangdingkun@cdutcm.edu.cn.
Chengdu University · CNChengdu Medical College · CNJiangxi University of Traditional Chinese Medicine · CNSichuan Academy of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81973493Sichuan Province Traditional Chinese Medicine Standardization Research Project 2019073
6 · The paper itself

Abstract

Phyllanthus emblica is a fruit widely consumed in subtropical areas, which is rich in polyphenols and other nutrients. There are increasing evidences that as a daily and nutritious fruit, it may have a positive role in controlling diabetic complications. According to the new study, its mechanisms include enhancing the functioning of insulin, reducing insulin resistance, activating the insulin-signaling pathway, protecting β-cells, scavenging free radicals, alleviating inflammatory reactions, and reducing the accumulation of advanced glycation end products. Owing to its few side effects, and low price, it should be easily accepted by patients and has potential for preventing diabetes. Taken together, Phyllanthus emblica may be an ideal fruit for controlling diabetic complications. This review highlights the latest findings of the role of Phyllanthus emblica in anti-diabetes and its complications, especially clarifies the molecular mechanism of the chemical components related to this effect, and prospects some existing problems and future research directions.

Indexed as

Diabetes Mellitus, Type 2Phyllanthus emblicaFruitHumansPlant ExtractsPolyphenolsPlant ExtractsPolyphenolsComplicationPhyllanthus emblicaType 2 diabetes mellitus

Identifiers

PMID33439332
OpenAlexW3119273783

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.