Evidence map›Paper›PMID 33445787›Full record

ArticleCells2021

IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors.

Leonardo Cristinziano, Remo Poto, Gjada Criscuolo, Anne Lise Ferrara, Maria Rosaria Galdiero, Luca Modestino, Stefania Loffredo, Amato de Paulis, Gianni Marone, Giuseppe Spadaro and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 51 citations in OpenAlex.

  1. Vascular remodeling in asthma: from mechanisms to precision medicine.Current opinion in allergy and clinical immunology · 2026
    Review
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  15. Potential Role of Moesin in Regulating Mast Cell Secretion.International journal of molecular sciences · 2023
    Review
  16. Mast Cells in Upper and Lower Airway Diseases: Sentinels in the Front Line.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Leonardo CristinzianoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-7835-2212
Remo PotoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Gjada CriscuoloDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Anne Lise FerraraDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-1839-8873
Maria Rosaria GaldieroDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Luca ModestinoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Stefania LoffredoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-5871-1898
Amato de PaulisDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Gianni MaroneDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-9849-4701
Giuseppe SpadaroDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Gilda VarricchiDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-9285-4657
World Health Organization - Italy · ITInstitute for Experimental Endocrinology and Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are strategically located in different compartments of human lung, where they play a role in several inflammatory disorders and cancer. Immunoglobulin superantigens (e.g., protein A of

Indexed as

Angiogenesis Inducing AgentsAntibodies, MonoclonalHumansImmunoglobulin EImmunoglobulin GInterleukin-33LungMast CellsNeovascularization, PhysiologicReceptors, IgESuperantigensVascular Endothelial Growth Factor AAngiogenesis Inducing AgentsAntibodies, MonoclonalImmunoglobulin EImmunoglobulin GInterleukin-33Receptors, IgESuperantigensVascular Endothelial Growth Factor AallergyasthmahistamineIL-33mast cellprotein Aprotein LsuperantigenVEGF-AVEGF-C

Identifiers

PMID33445787
PMCPMC7828291
OpenAlexW3119356936

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.