Evidence map›Paper›PMID 33446013›Full record

ArticleBioengineered2021

MicroRNA-146a-5p enhances T helper 17 cell differentiation via decreasing a disintegrin and metalloprotease 17 level in primary sjögren's syndrome.

Xiaoyan Wang, Shaojun Xin, Youqing Wang, Duo Ju, Quan Wu, Ye Qiu, Xuemin Niu, Wei Liu, Jianyou Li, Pengtian Ji

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  6. MiRNA-146a-A Key Player in Immunity and Diseases.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoyan WangClinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.ORCID 0000-0002-2655-9692
Shaojun XinClinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Youqing WangDepartment of Interventional Radiology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Duo JuDepartment of Interventional Radiology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Quan WuClinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Ye QiuClinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Xuemin NiuClinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Wei LiuDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Jianyou LiDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Pengtian JiDepartment of Interventional Radiology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University , Huzhou, China.
Huzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical practice, we found that microRNA (miR)-146a-5p is significantly up-regulated in peripheral blood mononuclear cells (PBMCs) of primary sjögren's syndrome (pSS) patients.

Indexed as

ADAM17 ProteinMicroRNAsSjogren's SyndromeTh17 CellsAdultCell DifferentiationHumansInterleukin-23Leukocytes, MononuclearMiddle AgedReceptors, InterleukinYoung AdultADAM17 ProteinADAM17 protein, humanIL23R protein, humanInterleukin-23MicroRNAsMIRN146 microRNA, humanReceptors, Interleukinadam17il-23/IL-23R signalingmir-146a-5pPrimary sjögren’s syndrometh17 cell differentiation

Identifiers

PMID33446013
PMCPMC8806215
OpenAlexW3123304303

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.