ArticleBMC genomics2021
Comparative mitogenome analyses uncover mitogenome features and phylogenetic implications of the subfamily Cobitinae.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed.
- Comparative Mitogenome Analyses Uncover Mitogenome Features and Phylogenetic Implications of the Rabbitfishes (Perciformes: Siganidae).Ecology and evolution · 2026Article
- The first complete mitochondrial genome of Zu cristatus (Bonelli, 1819) sheds new light on its phylogenetic position and molecular evolution.BMC zoology · 2025Article
- The Complete Mitochondrial Genome of the Deep-Dwelling GobyInternational journal of molecular sciences · 2025Article
- The complete mitochondrial genomes of the two species of Astyanax (Characiformes: Acestrorhamphidae) that occur in cenotes of the Yucatán Peninsula karst aquifer: comparative analyses and their taxonomic implications.Molecular biology reports · 2025Article
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- Whole-genome relaxed selection and molecular constraints in Triplophysa under adapted Qinghai-Tibetan Plateau.BMC genomics · 2025Article
- Comparative morphology and mitogenomics of freshwater mussels Koreosolenaia, Parvasolenaia, and Sinosolenaia (Bivalvia: Unionidae: Gonideinae).BMC genomics · 2024Article
- Characterization and phylogenetic implications of newly sequenced mitochondrial genomes of cobitid fish Acantopsis Rungthipae (Boyd, Nithirojpakdee & Page, 2017).Molecular biology reports · 2024Article
- Insights into the structural features and phylogenetic implications of the complete mitochondrial genome of Fasin rainbow fish (Melanotaenia fasinensis).BMC genomics · 2024Article
- Complete mitochondrial genome ofZooKeys · 2024Article
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- Comparative mitogenomic analyses unveil conserved and variable mitogenomic features and phylogeny of Chedrinae fish.Zoological research · 2022Article
- Comparative mitogenomes provide new insights into phylogeny and taxonomy of the subfamilyFrontiers in genetics · 2022Article
- Complete mitochondrial genomes of two catfishes (Siluriformes, Bagridae) and their phylogenetic implications.ZooKeys · 2022Article
- Comparative Analysis of Complete Mitogenomes of TwoZoological studies · 2022Article
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8 authors.
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Abstract
backgroundLoaches of Cobitinae, widely distributed in Eurasian continent, have high economic, ornamental and scientific value. However, the phylogeny of Cobitinae fishes within genera or family level remains complex and controversial. Up to now, about 60 Cobitinae mitogenomes had been deposited in GenBank, but their integrated characteristics were not elaborated.
resultsIn this study, we sequenced and analyzed the complete mitogenomes of a female Cobits macrostigma. Then we conducted a comparative mitogenome analysis and revealed the conserved and unique characteristics of 58 Cobitinae mitogenomes, including C. macrostigma. Cobitinae mitogenomes display highly conserved tRNA secondary structure, overlaps and non-coding intergenic spacers. In addition, distinct base compositions were observed among different genus and significantly negative linear correlation between AT% and AT-skew were found among Cobitinae, genus Cobitis and Pangio mitogenomes, respectively. A specific 3 bp insertion (GCA) in the atp8-atp6 overlap was identified as a unique feature of loaches, compared to other Cypriniformes fish. Additionally, all protein coding genes underwent a strong purifying selection. Phylogenetic analysis strongly supported the paraphyly of Cobitis and polyphyly of Misgurnus. The strict molecular clock predicted that Cobitinae might have split into northern and southern lineages in the late Eocene (42.11 Ma), furthermore, mtDNA introgression might occur (14.40 Ma) between ancestral species of Cobitis and ancestral species of Misgurnus.
conclusionsThe current study represents the first comparative mitogenomic and phylogenetic analyses within Cobitinae and provides new insights into the mitogenome features and evolution of fishes belonging to the cobitinae family.
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