Evidence map›Paper›PMID 33448307›Full record

ArticleInternational journal of molecular medicine2021

Mechanism of long non‑coding RNA metastasis‑associated lung adenocarcinoma transcript 1 in lipid metabolism and inflammation in heart failure.

Peng Zhao, Yunkai Wang, Luping Zhang, Jinhua Zhang, Ning Liu, Hongqiang Wang

Open access · hybridAbstract read
In one paragraph

Article in International journal of molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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  11. LncRNAs at the heart of development and disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Peng Zhao *Department of Cardiology I, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Yunkai Wang *Department of Cardiac Surgery ICU, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Luping ZhangDepartment of Reproductive Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Jinhua ZhangDepartment of Physical Examination, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Ning LiuDepartment of Obstetrics and Gynecology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Hongqiang WangDepartment of Cardiology II, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Yuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) is a serious threat to human health. Long noncoding RNAs (lncRNAs) are critical regulators of HF. The aim of the study was to investigate the molecular mechanism of MALAT1 in HF rats. MALAT1 expression was detected in serum of normal volunteers and HF patients, HF rats and isoproterenol (ISO)‑induced H9C2 cells, and its diagnostic value was evaluated in HF patients. Indexes related to cardiac functions and hemodynamics, myocardial injury, lipid metabolism, lipid oxidation, and inflammation were detected. Moreover, the downstream mechanism of MALAT1 was predicted and verified and

Indexed as

Lipid MetabolismAgedAnimalsCell LineFemaleHeart FailureHumansInflammationMaleMiddle AgedMyocarditisMyocardiumRatsRats, Sprague-DawleyRNA, Long NoncodingMALAT1 long non-coding RNA, humanMALAT1 long noncoding RNA, ratRNA, Long Noncodingheart failureinflammatory responseslipid metabolismlipid oxidationlong non‑coding RNA MALAT1microRNA‑532‑3p

Identifiers

PMID33448307
PMCPMC7834958
OpenAlexW3116927060

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.