Evidence map›Paper›PMID 33456556›Full record

Trial reportTheranostics2021

DRD1 downregulation contributes to mechanical stretch-induced lung endothelial barrier dysfunction.

Yan Wang, Yu-Jian Liu, Dun-Feng Xu, Hui Zhang, Chu-Fan Xu, Yan-Fei Mao, Zhou Lv, Xiao-Yan Zhu, Lai Jiang

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  8. Upregulation ofAnnals of translational medicine · 2022
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yan WangDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Yu-Jian LiuSchool of Kinesiology, The key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, 200438, China.
Dun-Feng XuDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Hui ZhangDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Chu-Fan XuDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Yan-Fei MaoDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Zhou LvDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
Xiao-Yan ZhuDepartment of Physiology, Navy Medical University, Shanghai, 200433, China.
Lai JiangDepartment of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
XinHua Hospital · CNShanghai University of Sport · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCyclic AMPDown-RegulationEndothelial CellsEndothelium, VascularHistone Deacetylase 6HumansLungMiceMice, KnockoutReceptors, Dopamine D1Respiration, ArtificialSignal TransductionStress, MechanicalTubulinVentilator-Induced Lung InjuryCyclic AMPDRD1 protein, humanHistone Deacetylase 6Receptors, Dopamine D1Tubulincyclic stretchDRD1mechanical ventilationmicrotubulepulmonary vascular endothelial cell

Identifiers

PMID33456556
PMCPMC7806475
OpenAlexW3118879807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.