Evidence map›Paper›PMID 33457135›Full record

ReviewCureus2020

The Association Between Hypertension and Cognitive Impairment, and the Role of Antihypertensive Medications: A Literature Review.

Nupur Mishra, Devyani Mohan, Sehrish Fuad, Deepak M Basavanagowda, Zaid A Alrashid, Arveen Kaur, Bindu Rathod, Sadia Nosher, Stacey E Heindl

Abstract readReview
In one paragraph

Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nupur MishraMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Devyani MohanSurgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sehrish FuadMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Deepak M BasavanagowdaPsychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Zaid A AlrashidNeurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Arveen KaurPsychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Bindu RathodPsychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sadia NosherFamily Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Stacey E HeindlMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular dementia (VD) is one of the leading causes of dementia, and hypertension is a known risk factor for VD. Hypertension treatment guidelines have previously discussed an optimal blood pressure goal to prevent further cardiovascular complications with long-term management. The treatment of hypertension can prevent stroke, kidney failure, and perhaps prevent cognitive decline as well. We reviewed studies that demonstrated an association between hypertension and cognitive impairment (CI). The role of antihypertensive medications (AHM) in preventing CI was also investigated. This topic is worth exploring as dementia has high healthcare costs and will become prominent as the population in the United States ages. We used the medical subject heading (MeSH) search strategy on Pubmed and reviewed 22 articles. The studies showed that there might be a link between hypertension, AHM, and CI. The studies did not suggest a superiority of any specific AHM class to prevent CI. Further research on optimal hypertension treatment goals to prevent cognitive impairment and dementia is recommended.

Indexed as

ace inhibitorsangiotensin receptor blockersantihypertensive medicationsblood pressurecalcium channel blockerscognitioncognitive impairmentdementiahypertensionthiazide diuretics

Identifiers

PMID33457135
PMCPMC7797448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.