Evidence map›Paper›PMID 33459113›Full record

ArticleCell cycle (Georgetown, Tex.)2021

LncRNA GAS6-AS2 promotes non-small-cell lung cancer cell proliferation via regulating miR-144-3p/ MAPK6 axis.

Guangjie Hou, Junfeng Yang, Jinxing Tang, Yi He

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guangjie HouHenan Provincial People's Hospital , Zhengzhou City, Henan Province, PR. China.
Junfeng YangHenan Provincial People's Hospital , Zhengzhou City, Henan Province, PR. China.
Jinxing TangHenan Provincial People's Hospital , Zhengzhou City, Henan Province, PR. China.
Yi HeHenan Provincial People's Hospital , Zhengzhou City, Henan Province, PR. China.
Henan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of a new long non-coding RNA GAS6-AS2 in non-small cell lung cancer (NSCLC) is not fully understood. In this study, GAS6-AS2 was identified, and its roles as well as mechanisms in regulating proliferation of NSCLCs cells were investigated. qRT-PCR was used to analyze GAS6-AS2, miR-144-3p, and MAPK6 expression. Protein expression was detected by Western blotting. Cell Counting Kit-8 (CCK8) assay was used to examine the cell proliferation ability. The interaction between GAS6-AS2 and miR-144-3p was confirmed by dual-luciferase reporter assay and RNA pull down assay. A xenograft model was constructed to monitor the mice NSCLC tumor growth

Indexed as

AdultAnimalsCarcinoma, Non-Small-Cell LungCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticGrowth Arrest-Specific Protein 6HumansIntercellular Signaling Peptides and ProteinsLung NeoplasmsMaleMiceMicroRNAsMiddle AgedGrowth Arrest-Specific Protein 6Intercellular Signaling Peptides and ProteinsMapk6 protein, mouseMicroRNAsMIRN144 microRNA, humanMitogen-Activated Protein Kinase 6RNA, Long NoncodingGAS6-AS2MAPK6miR-144-3pNSCLCproliferation

Identifiers

PMID33459113
PMCPMC7889124
OpenAlexW3124058587

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.