Evidence map›Paper›PMID 33466839›Full record

ArticleCancers2021

Genetic Screening for Potential New Targets in Chronic Myeloid Leukemia Based on Drosophila Transgenic for Human BCR-ABL1.

Marco Lo Iacono, Elisabetta Signorino, Jessica Petiti, Monica Pradotto, Chiara Calabrese, Cristina Panuzzo, Francesca Caciolli, Barbara Pergolizzi, Marco De Gobbi, Giovanna Rege-Cambrin and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Marco Lo IaconoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.ORCID 0000-0002-3936-4472
Elisabetta SignorinoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Jessica PetitiDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.ORCID 0000-0001-8640-2462
Monica PradottoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Chiara CalabreseDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Cristina PanuzzoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Francesca CaciolliDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Barbara PergolizziDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Marco De GobbiDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Giovanna Rege-CambrinDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Carmen FavaDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Claudia GiachinoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Enrico BraccoDepartment of Oncology, University of Turin, 10043 Turin, Italy.ORCID 0000-0003-3170-2817
Giuseppe SaglioDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Francesco FrassoniDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.
Daniela CilloniDepartment of Clinical and Biological Sciences, University of Turin, 10043 Turin, Italy.ORCID 0000-0001-6346-4791
University of Turin · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 10005Associazione Italiana per la Ricerca sul Cancro 10100Associazione Italiana per la Ricerca sul Cancro 9962
6 · The paper itself

Abstract

Chronic myeloid leukemia is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome that originates from the reciprocal translocation t(9;22)(q34;q11.2) and encodes for the constitutively active tyrosine kinase protein BCR-ABL1 from the

Indexed as

BCR-ABL1chronic myeloid leukemiaDrosophila melanogastergenetic screeningRab family

Identifiers

PMID33466839
PMCPMC7830713
OpenAlexW3119497447

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.