Evidence map›Paper›PMID 33468143›Full record

ReviewReproductive health2021

Impact of myo-inositol treatment in women with polycystic ovary syndrome in assisted reproductive technologies.

Philippe Merviel, Pandora James, Sarah Bouée, Mathilde Le Guillou, Camille Rince, Charlotte Nachtergaele, Véronique Kerlan

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Reproductive health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Philippe MervielFertility and ART Department, Brest University Hospital, 2 Avenue Foch, 29200, Brest, France. philippe.merviel@chu-brest.fr.ORCID http://orcid.org/0000-0003-0184-0880
Pandora JamesFertility and ART Department, Brest University Hospital, 2 Avenue Foch, 29200, Brest, France.
Sarah BouéeFertility and ART Department, Brest University Hospital, 2 Avenue Foch, 29200, Brest, France.
Mathilde Le GuillouFertility and ART Department, Brest University Hospital, 2 Avenue Foch, 29200, Brest, France.
Camille RinceFertility and ART Department, Brest University Hospital, 2 Avenue Foch, 29200, Brest, France.
Charlotte NachtergaeleEndocrinology and Metabolism Department, Brest University Hospital, Boulevard Tanguy Prigent, 29200, Brest, France.
Véronique KerlanEndocrinology and Metabolism Department, Brest University Hospital, Boulevard Tanguy Prigent, 29200, Brest, France.
Centre Hospitalier Régional Universitaire de Brest · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is marked in 30 to 40% by insulin resistance and hyperandrogenism. Myo-inositol (MI) increases insulin sensitivity, decreases hyperandrogenism and improves the menstrual cycle. Its effect during assisted reproductive technologies (ART) has been studied by many authors. We conducted a review of the literature on the impact of MI administration in PCOS women in assisted reproductive technologies. Myo-inositol is effective in normalizing ovarian function, improving oocyte and embryo quality in PCOS, however further evaluations by large multicentre randomized controlled trials are needed to assess the clinical pregnancy and live birth rates in ART.

Indexed as

Fertilization in VitroReproductive Techniques, AssistedFemaleHumansInositolPolycystic Ovary SyndromePregnancyPregnancy RateSperm Injections, IntracytoplasmicVitamin B ComplexInositolVitamin B ComplexEmbryo qualityIntracytoplasmic sperm injection (IVF-ICSI)In vitro fertilizationMyo-inositolPolycystic ovary syndrome (PCOS)Pregnancy

Identifiers

PMID33468143
PMCPMC7816413
OpenAlexW3123757349

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.