Evidence map›Paper›PMID 33471607›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2021

CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells.

Katja Koeppen, Amanda Nymon, Roxanna Barnaby, Zhongyou Li, Thomas H Hampton, Alix Ashare, Bruce A Stanton

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Extracellular vesicles secreted by primary human bronchial epithelial cells reduceAmerican journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Katja KoeppenDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Amanda NymonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Roxanna BarnabyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Zhongyou LiDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Thomas H HamptonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Alix AshareDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Dartmouth College · USDartmouth–Hitchcock Medical Center · US

Funding

Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI Robert Andrew Cramer · 2018 to 2026
$13.9M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Macrophage Pathogen Interactions in Regional Cystic Fibrosis Lung InflammationK24HL150453 · NHLBI · DARTMOUTH-HITCHCOCK CLINIC · PI ASHARE, ALIX · 2020 to 2024
$542k
Reproducible and FAIR Bioinformatics Analysis of Omics DataR25HG011447 · NHGRI · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI HAMPTON, THOMAS H, STANTON, BRUCE A. · 2021 to 2025
$399k
NHGRI NIH HHS R25 HG011447NHLBI NIH HHS K24 HL150453NHLBI NIH HHS R01 HL151385NIDDK NIH HHS P30 DK117469
6 · The paper itself

Abstract

Mutations in

Indexed as

Cells, CulturedCystic FibrosisCytokinesEpithelial CellsExtracellular VesiclesHumansImmunity, InnateInflammationLungMacrophagesPhagocytosisPseudomonas aeruginosaPseudomonas InfectionsCytokinesairway epithelial cellscystic fibrosiscytokine secretionexosomesmacrophages

Identifiers

PMID33471607
PMCPMC8238154
OpenAlexW3122894006

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.