Evidence map›Paper›PMID 33484599›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

Factors associated with hypertension among stroke-free indigenous Africans: Findings from the SIREN study.

Onoja M Akpa, Akinkunmi P Okekunle, Bruce Ovbiagele, Fred S Sarfo, Rufus O Akinyemi, Albert Akpalu, Kolawole W Wahab, Morenikeji Komolafe, Reginald Obiako, Lukman F Owolabi and 21 more

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  8. May Measurement Month 2022: an analysis of blood pressure screening results from Nigeria.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  9. Article
  10. May Measurement Month 2021: an analysis of blood pressure screening results from Nigeria.European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
  11. Non-cigarette Tobacco Use and Stroke Among West Africans: Evidence From the SIREN Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Onoja M AkpaDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0002-5201-512X
Akinkunmi P OkekunleDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0003-4825-4934
Bruce OvbiageleSchool of Medicine, Weill Institute for Neurosciences, University of California, San-Francisco, CA, USA.
Fred S SarfoDepartment of Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0001-7274-5093
Rufus O AkinyemiCenter for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Albert AkpaluDepartment of Community Health, University of Ghana Medical School, Accra, Ghana.
Kolawole W WahabDepartment of Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Morenikeji KomolafeDepartment of Medicine, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Reginald ObiakoDepartment of Medicine, Ahmadu Bello University, Zaria, Nigeria.
Lukman F OwolabiDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Godwin OgboleDepartment of Radiology, University of Ibadan, Ibadan, Nigeria.
Bimbo FawaleDepartment of Medicine, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Adekunle FakunleDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Christianah M AsaleyeDepartment of Medicine, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Cynthia O AkisanyaDepartment of Radiology, Federal Medical Centre, Abeokuta, Nigeria.
Dambatta A HamisuDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Luqman OgunjimiDepartment of Pharmacology and Therapeutics, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Shagamu, Nigeria.
Abiodun AdeoyeCenter for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Okechukwu OgahDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Dan LacklandMedical University of South Carolina, Charleston, SC, USA.
Ezinne O UvereDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Moyinoluwalogo M FaniyanDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Osahon J AsowataDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Osimhiarherhuo AdeleyeDepartment of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
Mayowa AridegbeDepartment of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
Taiwo OlunugaDepartment of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
Isah S YahayaDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Adeniji OlaleyeDepartment of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
Benedict Calys-TagoeDepartment of Community Health, University of Ghana Medical School, Accra, Ghana.
Mayowa O OwolabiCenter for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0003-1146-3070
SIREN Study as part of the H3Africa Consortium

Funding

H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
Phone-based Interventions under Nurse Guidance after Stroke II (PINGS II)R01HL152188 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE, SARFO, FRED STEPHEN · 2020 to 2024
$2.8M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NHLBI NIH HHS R01 HL152188NIH HHS 3U24HG009780-03S5NIH HHS R01HL152188NIH HHS R01NS107900NIH HHS R01NS107900-02S1NIH HHS R01NS115944-01NIH HHS U54HG007479NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS115944
6 · The paper itself

Abstract

Hypertension is one of the most important risk factors for stroke and cardiovascular diseases (CVD) globally. Understanding risk factors for hypertension among individuals with matching characteristics with stroke patients may inform primordial/primary prevention of hypertension and stroke among them. This study identified the risk factors for hypertension among community-dwelling stroke-free population in Ghana and Nigeria. Data for 4267 community-dwelling stroke-free controls subjects in the Stroke Investigative Research and Education Network (SIREN) study in Nigeria and Ghana were used. Participants were comprehensively assessed for sociodemographic, lifestyle and metabolic factors using standard methods. Hypertension was defined as a previous diagnosis by a health professional or use of an anti-hypertensive drug or mean systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Logistic regression analysis was used to estimate adjusted odds ratios (aOR) of hypertension and their 95% confidence intervals (CI) at p < .05. Overall, 56.7% of the participants were hypertensive with a higher proportion among respondents aged ≥60 years (53.0%). Factors including physical inactivity (aOR: 9.09; 95% CI: 4.03 to 20.53, p < .0001), diabetes (aOR: 2.70; CI: 1.91 to 3.82, p < .0001), being ≥60 years (aOR: 2.22; 95% CI: 1.78 to 2.77, p < .0001), and family history of CVD (aOR 2.02; CI: 1.59 to 2.56, p < .0001) were associated with increased aOR of hypertension. Lifestyle factors were associated with hypertension in the current population of community-dwelling stroke-free controls in west Africa. Community-oriented interventions to address sedentary lifestyles may benefit this population and reduce/prevent hypertension and stroke among them.

Indexed as

HypertensionStrokeGhanaHumansNigeriaRisk Factorshypertensionphysical inactivityrisk factorsSub-Saharan Africa

Identifiers

PMID33484599
PMCPMC8263562

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.