Evidence map›Paper›PMID 33490285›Full record

SynthesisJournal of diabetes research2021

Associations between Vascular Endothelial Growth Factor Gene Polymorphisms and Different Types of Diabetic Retinopathy Susceptibility: A Systematic Review and Meta-Analysis.

Liming Hu, Chunmei Gong, Xiaoping Chen, Honghao Zhou, Junxia Yan, Wenxu Hong

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. A case-control study of promoter and 5'UTR VEGF polymorphisms in diabetic retinopathy.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. VEGF-A related SNPs: a cardiovascular context.Frontiers in cardiovascular medicine · 2023
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liming HuShenzhen Center for Chronic Disease Control, 2021 Buxin Road, Luohu District Shenzhen 518020, China.ORCID https://orcid.org/0000-0002-0166-8585
Chunmei GongShenzhen Center for Chronic Disease Control, 2021 Buxin Road, Luohu District Shenzhen 518020, China.
Xiaoping ChenInstitute of Clinical Pharmacology, Central South University, Changsha, China.
Honghao ZhouInstitute of Clinical Pharmacology, Central South University, Changsha, China.
Junxia YanDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.ORCID https://orcid.org/0000-0001-6067-1613
Wenxu HongShenzhen Center for Chronic Disease Control, 2021 Buxin Road, Luohu District Shenzhen 518020, China.ORCID https://orcid.org/0000-0003-0260-1099
Central South University · CNShenzhen Nanshan Center for Chronic Disease Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular endothelial growth factor (

methodsElectronic databases PubMed, Embase, Web of Science, CNKI, and WANFANG DATA were searched for articles on the associations between

resultsA total of 13 and 18 studies analyzed the associations between

conclusionsRs2010963, rs833061, and rs699947 are associated with NPDR or PDR, which may be involved in the occurrence and development of DR.

Indexed as

Polymorphism, Single NucleotideAdultAgedAged, 80 and overDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyFemaleGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMiddle AgedVascular Endothelial Growth Factor AVitreoretinopathy, ProliferativeVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID33490285
PMCPMC7805525
OpenAlexW3120882304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.