ReviewInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2021
Cryptococcus neoformans: Sex, morphogenesis, and virulence.
Review in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 46 citations in OpenAlex.
- RcAlb-PepII Perturbs the Proteomic Profile ofMicroorganisms · 2026Article
- Ricin B lectin-like proteins mediate thermotolerance, cell wall integrity, and fungal virulence inCell surface (Amsterdam, Netherlands) · 2026Article
- Polymorphism and evolutionary origins of accessory chromosomes in the basidiomycete Tremella fuciformis.Nature communications · 2026Article
- Fungal Aerosol Exposure and Stage-Specific Variations in Taihang Chicken Houses During Winter.Microorganisms · 2025Article
- Different Patterns of Frequency, Lichen Specificity and Thallus Location Between the Yeast and Filamentous Phases of Two Lichen-Inhabiting Basidiomycetes.Environmental microbiology · 2025Article
- The complex evolution and genomic dynamics of mating-type loci in Cryptococcus and Kwoniella.PLoS biology · 2025Article
- Tracing the evolution and genomic dynamics of mating-type loci inbioRxiv : the preprint server for biology · 2025Article
- ER-mitochondrial crosstalk (ERMES) regulates cell wall composition in pathogenic fungi.Archives of microbiology · 2025Article
- Patterns and mechanisms of fungal genome plasticity.Current biology : CB · 2025Review
- The Hidden Fortress: A Comprehensive Review of Fungal Biofilms with Emphasis onJournal of fungi (Basel, Switzerland) · 2025Review
- Comprehensive whole metagenomics analysis uncovers microbial community and resistome variability across anthropogenically contaminated soils in urban and suburban areas of Tamil Nadu, India.Frontiers in microbiology · 2025Article
- Puf4 -mediated oxidative stress virulence attenuation inFrontiers in cellular and infection microbiology · 2025Article
- Research advances and public health strategies in China on WHO priority fungal pathogens.Mycology · 2025Review
- Cryptococcus neoformans in the sputum: a noninvasive diagnostic method.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Is Cryptococcus neoformans a pleomorphic fungus?Current opinion in microbiology · 2024Review
- Integrative Proteome and Metabolomics Analyses of Cryptococcus neoformans Responses to Melanin Substrates Niger seed and L-DOPA.Current microbiology · 2024Article
- Illuminating the Cryptococcus neoformans species complex: unveiling intracellular structures with fluorescent-protein-based markers.Genetics · 2024Article
- Preclinical Models for Cryptococcosis of the CNS and Their Characterization Using In Vivo Imaging Techniques.Journal of fungi (Basel, Switzerland) · 2024Review
- Genome-Wide Identification and Characterization of the Medium-Chain Dehydrogenase/Reductase Superfamily ofJournal of fungi (Basel, Switzerland) · 2024Article
- Ergosterol Is Critical for Sporogenesis inJournal of fungi (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis mainly in immunocompromised individuals. Different morphotypes enable this environmental fungus and opportunistic pathogen to adapt to different natural niches and exhibit different levels of pathogenicity in various hosts. It is well-recognized that C. neoformans undergoes bisexual or unisexual reproduction in vitro to generate genotypic, morphotypic, and phenotypic diversity, which augments its ability for adaptation. However, if and how sexual reproduction and the meiotic machinery exert any direct impact on the infection process is unclear. This review summarizes recent discoveries on the regulation of cryptococcal life cycle and morphogenesis, and how they impact cryptococcal pathogenicity. The potential role of the meiotic machinery on ploidy regulation during cryptococcal infection is also discussed. This review aims to stimulate further investigation on links between fungal morphogenesis, sexual reproduction, and virulence.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.