Evidence map›Paper›PMID 33498280›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Weighted Gene Co-Expression Network Analysis Identifies Key Modules and Hub Genes Associated with Mycobacterial Infection of Human Macrophages.

Lu Lu, RanLei Wei, Sanjib Bhakta, Simon J Waddell, Ester Boix

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Lu LuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 610000, China.ORCID 0000-0002-0960-1529
RanLei WeiLaboratory of Omics Technology and Bioinformatics, West China Hospital, Sichuan University, Chengdu 610017, China.
Sanjib BhaktaMycobacteria Research Laboratory, Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck, University of London, London WC1E 7HX, UK.ORCID 0000-0002-1165-9295
Simon J WaddellGlobal Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton BN1 9PX, UK.
Ester BoixDepartment of Biochemistry and Molecular Biology, Faculty of Biosciences, Universitat Autonoma de Barcelona, 08290 Cerdanyola del Vallès, Spain.ORCID 0000-0003-1790-2142
Universitat Autònoma de Barcelona · ESBrighton and Sussex Medical School · GBInstitute of Structural and Molecular Biology · GBSichuan University · CN

Funding

Ministerio de Ciencia e Innovación PID2019-106123GB-I00
6 · The paper itself

Abstract

Tuberculosis (TB) is still a leading cause of death worldwide. Treatments remain unsatisfactory due to an incomplete understanding of the underlying host-pathogen interactions during infection. In the present study, weighted gene co-expression network analysis (WGCNA) was conducted to identify key macrophage modules and hub genes associated with mycobacterial infection. WGCNA was performed combining our own transcriptomic results using

Indexed as

macrophagemycobacteriumnetwork analysistranscriptomeWGCNA

Identifiers

PMID33498280
PMCPMC7909288
OpenAlexW3124247789

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.