Evidence map›Paper›PMID 33498379›Full record

ArticleJournal of clinical medicine2021

Body Mass Index and Disease Activity in Chronic Inflammatory Rheumatic Diseases: Results of the Cardiovascular in Rheumatology (Carma) Project.

Jesús A Valero-Jaimes, Ruth López-González, María A Martín-Martínez, Carmen García-Gómez, Fernando Sánchez-Alonso, Jesús T Sánchez-Costa, Carlos González-Juanatey, Eva Revuelta-Evrad, César Díaz-Torné, Cruz Fernández-Espartero and 13 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 18 institutions in 2 countries.

Jesús A Valero-JaimesDivision of Rheumatology, Hospital Universitario de Donosti, 20014 San Sebastián, Spain.
Ruth López-GonzálezDivision of Rheumatology, Hospital Universitario Hospital General Virgen de la Concha, 49022 Zamora, Spain.
María A Martín-MartínezResearch Unit of Spanish Society of Rheumatology, 28001 Madrid, Spain.
Carmen García-GómezDivision of Rheumatology, Consorci Sanitari de Terrassa, Terrassa, 08191 Barcelona, Spain.
Fernando Sánchez-AlonsoResearch Unit of Spanish Society of Rheumatology, 28001 Madrid, Spain.
Jesús T Sánchez-CostaResearch Unit of Spanish Society of Rheumatology, 28001 Madrid, Spain.
Carlos González-JuanateyDivision of Cardiology, Hospital Universitario Lucus Augusti, 27003 Lugo, Spain.
Eva Revuelta-EvradDivision of Rheumatology, Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, Spain.
César Díaz-TornéDivision of Rheumatology, Hospital de la Santa Creu I Santa Pau, 08041 Barcelona, Spain.
Cruz Fernández-EsparteroDivision of Rheumatology, Hospital Universitario de Móstoles, 28935 Madrid, Spain.
Carolina Pérez-GarcíaDivision of Rheumatology, Hospital del Mar, 08003 Barcelona, Spain.
Vicenç Torrente-SegarraDivision of Rheumatology, Hospital Comarcal Alt Penedès Garraf, 08720 Barcelona, Spain.ORCID 0000-0001-6597-3565
Ginés Sánchez-NievasDivision of Rheumatology, Complejo Hospitalario Universitario de Albacete, 02006 Albacete, Spain.
Trinidad Pérez-SandovalDivision of Rheumatology, Complejo Asistencial Universitario de León, 24071 León, Spain.
Pilar Font-UgaldeDivision of Rheumatology, Hospital Universitario Reina Sofía, 14004 Córdoba, Spain.ORCID 0000-0002-0811-9079
María L García-VivarDivision of Rheumatology, Hospital Universitario Basurto, 48013 Bilbao, Spain.
Elena AurrecoecheaDivision of Rheumatology, Hospital de Sierrallana, 39300 Santander, Spain.ORCID 0000-0001-6789-7236
Olga Maiz-AlonsoDivision of Rheumatology, Hospital Universitario de Donosti, 20014 San Sebastián, Spain.
Ramón Valls-GarcíaDivision of Rheumatology, Hospital Universitario de Palamós, 17230 Barcelona, Spain.
José A Miranda-FilloyDivision of Rheumatology, Hospital Universitario Lucus Augusti, 27003 Lugo, Spain.
Javier LlorcaUniversity of Cantabria and CIBER Epidemiología y Salud Pública (CIBERESP), 39005 Santander, Spain.
Santos CastañedaDivision of Rheumatology, Hospital Universitario de la Princesa, IIS-Princesa, EPID-Future, Universidad Autónoma de Madrid (UAM), 28006 Madrid, Spain.
Miguel A Gonzalez-GayDivision of Rheumatology, Hospital Universitario Marqués de Valdecilla, University of Cantabria, 39008 Santander, Spain.ORCID 0000-0002-7924-7406
Spanish Society of Hematology and Hemotherapy · ESBiogipuzkoa Health Research Institute · ESHospital Universitario Lucus Augusti · ESUniversidad de Cantabria · ESComplejo Asistencial Universitario de Palencia · ESComplejo Hospitalario Universitario de Albacete · ESConsorci Sanitari de Terrassa · ESHospital Comarcal de Inca · ESHospital de Basurto · ESHospital Del Mar · ESHospital de Palamós · ESHospital de Sant Pau · ESHospital General Universitario de Ciudad Real · ESHospital Sierrallana · ESHospital Universitario de La Princesa · ESHospital Universitario de Móstoles · ESHospital Universitario Reina Sofía · ESHospital Virgen de la Concha · ES

Funding

Abbvie, Spain. Fondo de Investigaciones Sanitarias (FIS); Instituto de Salud Carlos III" (ISCIII) (Spain), co-funded by FEDER unrestricted grant; PI06/0024, PS09/00748, PI12/00060, PI15/00525, PI18/00043; RD12/0009/0013 and RD16/0012 (RIER).
6 · The paper itself

Abstract

objectiveSince obesity has been associated with a higher inflammatory burden and worse response to therapy in patients with chronic inflammatory rheumatic diseases (CIRD), we aimed to confirm the potential association between body mass index (BMI) and disease activity in a large series of patients with CIRDs included in the Spanish CARdiovascular in rheuMAtology (CARMA) registry.

methodsBaseline data analysis of patients included from the CARMA project, a 10-year prospective study of patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA) attending outpatient rheumatology clinics from 67 Spanish hospitals. Obesity was defined when BMI (kg/m

resultsData from 2234 patients (775 RA, 738 AS, and 721 PsA) were assessed. The mean ± SD BMI at the baseline visit were: 26.9 ± 4.8 in RA, 27.4 ± 4.4 in AS, and 28.2 ± 4.7 in PsA. A positive association between BMI and disease activity in patients with RA (β = 0.029; 95%CI (0.01- 0.05);

conclusionsBMI is associated with disease activity in RA and PsA, but not in AS. Given that obesity is a potentially modifiable factor, adequate control of body weight can improve the outcome of patients with CIRD and, therefore, weight control should be included in the management strategy of these patients.

Indexed as

ankylosing spondylitisbody mass indexobesitypsoriatic arthritis and disease activityrheumatoid arthritis

Identifiers

PMID33498379
PMCPMC7864025
OpenAlexW3124063281

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.