Evidence map›Paper›PMID 33501463›Full record

ArticlemedRxiv : the preprint server for health sciences2021

Cortical Mechanisms of Visual Hypersensitivity in Women at Risk for Chronic Pelvic Pain.

Matthew J Kmiecik, Frank F Tu, Rebecca L Silton, Katlyn E Dillane, Genevieve E Roth, Steven E Harte, Kevin M Hellman

Registry-linked trialOpen access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06861920 (Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06861920 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea (NSAID HEAL)

TypeinterventionalSponsorEndeavor HealthRan2025 to 2030Enrolled600ConditionsDysmenorrhea, Chronic Pelvic Pain, Pelvic PainArmsNaproxen Sodium 550mg, Placebo, Extended Release Acetaminophen (650 mg)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Matthew J KmiecikDepartment of Ob/Gyn, NorthShore University HealthSystem, Evanston, IL, United States.
Frank F TuDepartment of Ob/Gyn, NorthShore University HealthSystem, Evanston, IL, United States.
Rebecca L SiltonDepartment of Psychology, Loyola University Chicago, Chicago, IL, United States.
Katlyn E DillaneDepartment of Ob/Gyn, NorthShore University HealthSystem, Evanston, IL, United States.
Genevieve E RothDepartment of Ob/Gyn, NorthShore University HealthSystem, Evanston, IL, United States.
Steven E HarteChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI.
Kevin M HellmanDepartment of Ob/Gyn, NorthShore University HealthSystem, Evanston, IL, United States.
NorthShore University HealthSystem · USLoyola University Chicago · USUniversity of Michigan · US

Funding

Deciphering the hormonal and nociceptive mechanisms underlying bladder painR01DK100368 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI Frank Fu-sheng Tu · 2014 to 2026
$5.2M
Mechanistic Characterization of Uterine Pain (M-CUP) to improve diagnosis and treatment for dysmenorrheaR01HD098193 · NICHD · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI HELLMAN, KEVIN · 2019 to 2023
$2.8M
NICHD NIH HHS R01 HD098193NIDDK NIH HHS R01 DK100368
6 · The paper itself

Abstract

Multisensory hypersensitivity (MSH), which refers to persistent discomfort across sensory modalities, is a risk factor for chronic pain. Developing a better understanding of the neural contributions of disparate sensory systems to MSH may clarify its role in the development of chronic pain. We recruited a cohort of women (

Identifiers

PMID33501463
PMCPMC7836135
OpenAlexW3109376593

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.