ArticleCirculation2021
Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.
Article in Circulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 15 registered trials, which are not on this map. Cited by 3,024 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Acupressure on Pain, Anxiety and Vital Signs in Patients With Coronary Angiography: A Randomized Controlled Study
Word Retrieval in the Wild: An Ecological Momentary Assessment Pilot Study in People With Post-Stroke Aphasia
Feasibility Study to Increase Resilience Through an At-home Virtual Exercise Training (Res-ET) Intervention Using Inspiratory Muscle Strength Training (IMST)
Evaluating the Safety and Efficacy of Atrial Shunt Implantation Systems for the Treatment of Patients With Chronic Left Heart Failure Prospective, Multicenter, Single-group Target Value Clinical Trials
Evaluation of the Progression of Disease and Health-related Quality of Life in Ambulatory Heart Failure Patients: A Local Clinic-based Registry
Stroke Recovery Program-Cardiac Rehabilitation of Stroke Survivors
HEART (Heart Failure Exercise and Resistance Training) Camp Connect: Promoting Adherence to Exercise in Adults With Heart Failure With Preserved Ejection Fraction
The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
Marijuana and Acute Risk of Arrhythmia- Joint Abstinence and Exposure
Study of The Association Between Triglyceride Glucose Index and Severity of Coronary Artery Disease
The Effect of Ankle Foot Orthesis on Task-oriented Treatment in Stroke
Uppsala Self-SCREENing of Heart Failure Study
Individualized Closed-Loop Neuromodulation With Repetitive Transcranial Magnetic Stimulation Synchronized Task Training for Upper Limb Motor Dysfunction in Stroke Patients
The Effect of a Nurse-led Daily Weight Monitoring Intervention (Wake and Weigh) on Heart Failure Quality of Life and Self-care
The PALL-VAD Study: Palliative Care Intervention to Improve Health Related Quality of Life for Patients With Heart Failure on Long-Term LVAD Support: A Pilot, Prospective, Randomized Trial
Who cites it
3,024 citing papers in PubMed, 10 syntheses or guidelines pooled it, 5,571 citations in OpenAlex.
- Comparative efficacy and safety of apixaban and rivaroxaban versus warfarin in atrial fibrillation patients with end-stage renal disease: a systematic review and meta-analysis.Renal failure · 2026Pooled it
- Combined transcranial direct current stimulation and mirror therapy for upper limb rehabilitation in patients with stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Diagnostic accuracy of coronary CT angiography versus invasive coronary angiography for detecting coronary artery disease: a systematic review and Bayesian meta-analysis.BMC medical imaging · 2026Pooled it
- Cimlanod, a Second-Generation Nitroxyl Donor, in Heart Failure with Reduced Ejection Fraction: A Meta-Analysis of Hemodynamic Efficacy and Safety Profile.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026Pooled it
- Frailty and postoperative complications in elderly patients undergoing cardiac surgery: a systematic review and meta-analysis.BMC geriatrics · 2026Pooled it
- Efficacy and safety of vericiguat across the spectrum of heart failure: a systematic review and updated meta‑analysis of randomized controlled trials.European journal of clinical pharmacology · 2026Pooled it
- Cardiovascular effects of exercise training in spontaneously hypertensive rats: A systematic review and meta-analysis.Physiological reports · 2026Pooled it
- Risk factors for small vessel disease in adults with atherosclerosis: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Does Time to Achieve a Targeted Body Temperature Matter for Survivors of Cardiac Arrest? A Systematic Review and Meta-Analysis.Critical care medicine · 2026Pooled it
- Risk prediction models for malignant cerebral edema after endovascular therapy in patients with acute anterior circulation large vessel occlusion stroke: a systematic review and meta-analysis.Frontiers in neurology · 2026Pooled it
- Heliox ventilation promotes pulmonary circulation and cardiac function in elderly hypertensive patients: a randomized controlled trial.Medical gas research · 2026Trial
- Care Navigation, Self-Measured Blood Pressure, and Health Coaching for Postpartum Care: A Randomized Clinical Trial.JAMA network open · 2026Trial
- A pilot randomized clinical trial of gamification to increase medication adherence.American heart journal · 2026 · on this mapTrial
- Effectiveness of telemonitoring on clinical outcomes in patients with heart failure: a randomized clinical trial.Scientific reports · 2026Trial
- Trial
- Impact of Self-Management Education on Self-care Behaviors, Quality of Life and, Readmission in Heart Failure Patients: A Randomized Controlled Trial.International journal of community based nursing and midwifery · 2026Trial
- Effect of Tai Chi Yunshou motor imagery training on upper limb motor dysfunction with stroke patients.BMC complementary medicine and therapies · 2026Trial
- Trajectory of longitudinal lending discrimination modifies the efficacy of a skills-based intervention in stroke survivors.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2026Trial
- Knowledge on hypertension among hypertensive stroke survivors in Ghana: A cross-sectional, multicenter study.Equity neuroscience · 2026Article
- Differences of plaque burden measures on CCTA in younger men and women.American journal of preventive cardiology · 2026Article
2,964 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors.
Funding
Abstract
backgroundThe American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs).
methodsThe American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2021 Statistical Update is the product of a full year's worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year's edition includes data on the monitoring and benefits of cardiovascular health in the population, an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, the global burden of cardiovascular disease, and further evidence-based approaches to changing behaviors related to cardiovascular disease.
resultsEach of the 27 chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics.
conclusionsThe Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.