ArticleeLife2021
ATP activation of peritubular cells drives testicular sperm transport.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- Cell type-specific Ca2+ signals govern mouse seminiferous tubule physiology.PLoS biology · 2026Article
- A rapid and robust translational model for testicular aging research.Histochemistry and cell biology · 2026Article
- Comparative analysis of mRNA and circRNA expression profiles and interaction networks in testicular tissues of Mongolian horses before and after sexual maturity.BMC genomics · 2026Article
- Integrated Analysis of Testicular Histology, Sperm Quality, and Gene Expression (Animals : an open access journal from MDPI · 2026Article
- High-altitude hypoxia and male reproductive dysfunction: testicular oxygen homeostasis, microenvironmental injury and spermatogonial niche vulnerability.Frontiers in endocrinology · 2026Review
- Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function.Science advances · 2025Article
- Toxic Effects of Methamphetamine on Reproductive Systems, Embryo Development, and Newborns: An Evidence-based Review.Current medicinal chemistry · 2025Review
- Sertoli cells as a hub in testicular development and male reproductive.Frontiers in cell and developmental biology · 2025Review
- Gonadotropins differentially regulate testicular cell adhesion and junctional complexes during flatfish spermiogenesis through the oxytocin and relaxin signaling pathways.Frontiers in cell and developmental biology · 2025Article
- From stress signals to fertility challenges: the role of damage-associated molecular patterns in male reproduction.Frontiers in immunology · 2025Review
- Identification of Catecholamine and Drug Target αJournal of clinical medicine · 2024Article
- Deficiency ofInternational journal of molecular sciences · 2024Article
- Insights on Platelet-Derived Growth Factor Receptor α-Positive Interstitial Cells in the Male Reproductive Tract.International journal of molecular sciences · 2024Review
- A revised conceptual framework for mouse vomeronasal pumping and stimulus sampling.Current biology : CB · 2024Article
- In vivo dynamic volumetric imaging of mouse testis and epididymis with optical coherence tomography†.Biology of reproduction · 2024Article
- Biogenic amines in the testis: sources, receptors and actions.Frontiers in endocrinology · 2024Review
- Optical coherence tomography for dynamic investigation of mammalian reproductive processes.Molecular reproduction and development · 2023Review
- SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse.Nature communications · 2022Article
- The Molecular Signature of Human Testicular Peritubular Cells Revealed by Single-Cell Analysis.Cells · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spermatogenesis, the complex process of male germ cell proliferation, differentiation, and maturation, is the basis of male fertility. In the seminiferous tubules of the testes, spermatozoa are constantly generated from spermatogonial stem cells through a stereotyped sequence of mitotic and meiotic divisions. The basic physiological principles, however, that control both maturation and luminal transport of the still immotile spermatozoa within the seminiferous tubules remain poorly, if at all, defined. Here, we show that coordinated contractions of smooth muscle-like testicular peritubular cells provide the propulsive force for luminal sperm transport toward the rete testis. Using a mouse model for in vivo imaging, we describe and quantify spontaneous tubular contractions and show a causal relationship between peritubular Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.