Evidence map›Paper›PMID 33505878›Full record

ArticleTzu chi medical journal

Prevalence and predictors of low bone mineral density in treatment-naive HIV-infected patients and its correlation with CD4 cell counts.

Pulin Kumar Gupta, Sanchit Singh, Subodh Kumar Mahto, Ankita Sheoran, Umesh Chand Garga, Ashok Kumar Lal, Piyush Jain, Sujata Elizabeth Mathews

Open access · diamondAbstract read
In one paragraph

Article in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pulin Kumar GuptaDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Sanchit SinghDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Subodh Kumar MahtoDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Ankita SheoranDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Umesh Chand GargaDepartment of Radiology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Ashok Kumar LalDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Piyush JainDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Sujata Elizabeth MathewsDepartment of Medicine, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHIV virtually affects every organ system of the body. The skeletal system is no exception, and antiretroviral therapy (ART) has been implicated in bone diseases. However, not many studies have been done to evaluate bone disease in treatment (ART) naive HIV-infected patients, and hence, the present study was executed. MATERIALS AND

methodsOne hundred and twenty HIV-infected ART-naive patients and 80 age- and sex-matched healthy controls were recruited for this study. A thorough history and physical examination was done followed by laboratory investigations after an overnight fasting. Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry scan at the level of lumbar spine, femur, and forearm.

resultsOf 120 ART-naive HIV-infected cases, the prevalence of osteoporosis and osteopenia was 13% and 41%, respectively, as compared to 0% and 17.5% in controls (

conclusionBone diseases such as osteoporosis and osteopenia characterized by low BMD are very common in HIV-infected patients. Virus

Indexed as

Bone mineral densityCD4 countsHIV/acquired immunodeficiency syndromeOsteopeniaOsteoporosis

Identifiers

PMID33505878
PMCPMC7821822
OpenAlexW3015516279

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.