Evidence mapPaperPMID 33506132Full record

ReviewHeliyon2021

Time-in-range as a target in type 2 diabetes: An urgent need.

Banshi Saboo, Jothydev Kesavadev, Arun Shankar, Meera B Krishna, Shruti Sheth, Vidisha Patel, Gopika Krishnan

Abstract readReview
In one paragraph

Review in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. To What Extent Is HbJournal of clinical medicine · 2024
    Article
  12. Insulin Therapy for the Management of Diabetes Mellitus: A Narrative Review of Innovative Treatment Strategies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
  13. Expert Consensus Recommendations on Time in Range for Monitoring Glucose Levels in People with Diabetes: An Indian Perspective.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
  14. Article
  15. Article
  16. The Role of Glycemic Variability in Cardiovascular Disorders.International journal of molecular sciences · 2021
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Banshi SabooDiaCare, Ahmedabad, Gujarat, India.
Jothydev KesavadevJothydev's Diabetes Research Centre, Mudavanmugal, Thiruvananthapuram, Kerala, India.
Arun ShankarJothydev's Diabetes Research Centre, Mudavanmugal, Thiruvananthapuram, Kerala, India.
Meera B KrishnaJothydev's Diabetes Research Centre, Mudavanmugal, Thiruvananthapuram, Kerala, India.
Shruti ShethDiaCare, Ahmedabad, Gujarat, India.
Vidisha PatelDiaCare, Ahmedabad, Gujarat, India.
Gopika KrishnanJothydev's Diabetes Research Centre, Mudavanmugal, Thiruvananthapuram, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Time-in-range emerged as a valuable blood glucose metric, 'beyond HbA1c' for a deeper insight into glycemic control in people with diabetes. It denotes the proportion of time that a person's glucose level remains within the desired target range (usually 70-180 mg/dL or 3.9-10.0 mmol/L). Though clinical targets in the current recommendations for type 1 and type 2 diabetes are close enough, their clinical profiles and prevalences are quite different. Type 2 diabetes is the commonest form of diabetes. Many clinical trials have challenged the usefulness of HbA1c as a glycemic target for Type 2 diabetes mellitus. On account of the higher prevalence and complications of type 2 diabetes, more outcomes-based studies are needed to associate time-in-range with its ongoing risk. These studies strongly support the dependability of time-in-range to identify patients with elevated risk in type 2 diabetes. We discuss the utility of time-in-range, a new metric of continuous glucose monitoring as an outcome measure to correlate with type 2 diabetes risks and complications and to analyze the effectiveness of type 2 diabetes management. This approach may support the use of time-in-range as a metric for long-term health outcomes in the type 2 diabetes population.

Indexed as

Continuous glucose monitoringHbA1cTime-in-rangeType 2 diabetes

Identifiers

PMID33506132
PMCPMC7814148

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.